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Revolutionizing biomedicine: Aptamer-based nanomaterials and nanodevices for therapeutic applications.
Urmi, Rajkumari; Banerjee, Pallabi; Singh, Manisha; Singh, Risha; Chhillar, Sonam; Sharma, Neha; Chandra, Anshuman; Singh, Nagendra; Qamar, Imteyaz.
Afiliación
  • Urmi R; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Banerjee P; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Singh M; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Singh R; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Chhillar S; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Sharma N; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Chandra A; School of Physical Sciences, Jawaharlal Nehru University, New Delhi, 110067, India.
  • Singh N; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
  • Qamar I; School of Biotechnology, Gautam Buddha University, Greater Noida, U.P. 201312, India.
Biotechnol Rep (Amst) ; 42: e00843, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38881649
ABSTRACT
With the progress in two distinct areas of nanotechnology and aptamer identification technologies, the two fields have merged to what is known as aptamer nanotechnology. Aptamers have varying properties in the biomedical field include their small size, non-toxicity, ease of manufacturing, negligible immunogenicity, ability to identify a wide range of targets, and high immobilizing capacity. Nevertheless, aptamers can utilize the distinct characteristics offered by nanomaterials like optical, magnetic, thermal, electronic properties to become more versatile and function as a novel device in diagnostics and therapeutics. This engineered aptamer conjugated nanomaterials, in turn provides a potentially new and unique properties apart from the pre-existing characteristics of aptamer and nanomaterials, where they act to offer wide array of applications in the biomedical field ranging from drug targeting, delivery of drugs, biosensing, bioimaging. This review gives comprehensive insight of the different aptamer conjugated nanomaterials and their utilization in biomedical field. Firstly, it introduces on the aptamer selection methods and roles of nanomaterials offered. Further, different conjugation strategies are explored in addition, the class of aptamer conjugated nanodevices being discussed. Typical biomedical examples and studies specifically, related to drug delivery, biosensing, bioimaging have been presented.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biotechnol Rep (Amst) Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Biotechnol Rep (Amst) Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: Países Bajos