Your browser doesn't support javascript.
loading
Incidence and Remission of Post-Surgical Cystoid Macular Edema Following Cataract Surgery in Eyes With Intraocular Inflammation.
Gangaputra, Sapna; Newcomb, Craig; Ying, Gui-Shuang; Groth, Sylvia; Fitzgerald, Tonetta D; Artornsombudh, Pichaporn; Kothari, Srishti; Pujari, Siddharth S; Jabs, Douglas A; Levy-Clarke, Grace A; Nussenblatt, Robert B; Rosenbaum, James T; Sen, H Nida; Suhler, Eric B; Thorne, Jennifer E; Bhatt, Nirali P; Foster, C Stephen; Dreger, Kurt A; Buchanich, Jeanine M; Kempen, John H.
Afiliación
  • Gangaputra S; From the Vanderbilt Eye Institute (S.G., S.G.), Vanderbilt University Medical Center, Nashville, Tennessee, USA. Electronic address: sapna.gangaputra@vumc.org.
  • Newcomb C; Center for Clinical Epidemiology and Biostatistics (C.N.), Department of Biostatistics and Epidemiology, The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Ying GS; Department of Ophthalmology (G.-S.Y., T.D.F., S.K., N.P.B., K.A.D.), The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Groth S; From the Vanderbilt Eye Institute (S.G., S.G.), Vanderbilt University Medical Center, Nashville, Tennessee, USA.
  • Fitzgerald TD; Department of Ophthalmology (G.-S.Y., T.D.F., S.K., N.P.B., K.A.D.), The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Artornsombudh P; Department of Ophthalmology (P.A.), Somdech Phra Pinkloa Hospital, Royal Thai Navy, Bangkok, Thailand; Department of Ophthalmology (P.A.), Chulalongkorn University, Bangkok, Thailand.
  • Kothari S; Department of Ophthalmology (G.-S.Y., T.D.F., S.K., N.P.B., K.A.D.), The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA; Massachusetts Eye Research and Surgery Institution (S.K., C.S.F.), Waltham, Massachusetts, USA.
  • Pujari SS; Siddharth Netralaya Superspecialty Eye Hospital (S.S.P.), Belgaum, Karnataka, India.
  • Jabs DA; Wilmer Eye Institute (D.A.J., J.E.T.), The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Clinical Trials and Evidence Synthesis (D.A.J., J.E.T.), Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Levy-Clarke GA; Department of Ophthalmology and Visual Sciences (G.A.L.-C.), West Virginia University, Morgantown, West Virginia, USA.
  • Nussenblatt RB; Laboratory of Immunology (R.B.N.), National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Rosenbaum JT; Department of Ophthalmology (J.T.R., E.B.S.), Oregon Health and Science University, Portland, Oregon, USA; Department of Medicine (J.T.R.), Oregon Health and Science University, Portland, Oregon, USA; Legacy Devers Eye Institute (J.T.R.), Portland, Oregon, USA.
  • Sen HN; Department of Ophthalmology (H.N.S.), George Washington University, Washington, DC, USA; Janssen Retina Global Clinical Development (H.N.S.), Princeton, New Jersey, USA.
  • Suhler EB; Department of Ophthalmology (J.T.R., E.B.S.), Oregon Health and Science University, Portland, Oregon, USA; Portland Veteran's Affairs Medical Center (E.B.S.), Portland, Oregon, USA.
  • Thorne JE; Wilmer Eye Institute (D.A.J., J.E.T.), The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Center for Clinical Trials and Evidence Synthesis (D.A.J., J.E.T.), Department of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.
  • Bhatt NP; Department of Ophthalmology (G.-S.Y., T.D.F., S.K., N.P.B., K.A.D.), The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Foster CS; Massachusetts Eye Research and Surgery Institution (S.K., C.S.F.), Waltham, Massachusetts, USA; Department of Ophthalmology and Schepens Eye Research Institute (C.S.F., J.H.K.), Massachusetts Eye and Ear Infirmary; and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA.
  • Dreger KA; Department of Ophthalmology (G.-S.Y., T.D.F., S.K., N.P.B., K.A.D.), The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania, USA; Department of Population, Family, and Reproductive Health (K.A.D.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryl
  • Buchanich JM; Center for Occupational Biostatistics and Epidemiology (J.M.B.), University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.
  • Kempen JH; Department of Ophthalmology and Schepens Eye Research Institute (C.S.F., J.H.K.), Massachusetts Eye and Ear Infirmary; and Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA; Sight for Souls (J.H.K.), Bellevue, Washington, USA; MCM Eye Unit (J.H.K.), MyungSung Christian
Am J Ophthalmol ; 267: 182-191, 2024 Nov.
Article en En | MEDLINE | ID: mdl-38880375
ABSTRACT

PURPOSE:

To evaluate the incidence, remission, and relapse of post-surgical cystoid macular edema (PCME) following cataract surgery in inflammatory eye disease.

METHODS:

A total of 1859 eyes that had no visually significant macular edema prior to cataract surgery while under tertiary uveitis management were included. Standardized retrospective chart review was used to gather clinical data. Univariable and multivariable logistic regression models with adjustment for inter-eye correlations were performed.

RESULTS:

PCME causing VA 20/50 or worse was reported in 286 eyes (15%) within 6 months of surgery. Adults age 18-64 years as compared to children (adjusted odds ratio [aOR] = 2.42, for ages 18 to 44 years and aOR = 1.93 for ages 45 to 64 years, overall P = .02); concurrent use of systemic immunosuppression (conventional aOR 1.53 and biologics aOR = 2.68, overall P = .0095); preoperative VA 20/50 or worse (overall P < .0001); cataract surgery performed before 2000 (overall P = .03) and PMCE in fellow eye (aOR = 3.04, P = .0004) were associated with development of PCME within 6 months of cataract surgery. PCME resolution was seen in 81% of eyes at 12 months and 91% of eyes at 24 months. CME relapse was seen in 12% eyes at 12 months and 19% eyes at 24 months.

CONCLUSIONS:

PCME occurs frequently in uveitic eyes undergoing cataract surgery; however, most resolve within a year. CME recurrences likely are due to the underlying disease process and not relapses of PCME.
Asunto(s)
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Agudeza Visual / Edema Macular Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Ophthalmol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Complicaciones Posoperatorias / Agudeza Visual / Edema Macular Límite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: En Revista: Am J Ophthalmol Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos