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Association between Lipoprotein(a) concentration and adverse cardiac events in patients with coronary artery disease: An observational cohort study.
Amin, Navaneeth; Devasia, Tom; Kamath, Shobha Ullas; Paramasivam, Ganesh; Shetty, Prasad Narayana; Singh, Ajit; Prakash N S, Ganesha.
Afiliación
  • Amin N; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: navaneeth.kmc@learner.manipal.edu.
  • Devasia T; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: tom.devasia@manipal.edu.
  • Kamath SU; Department of Biochemistry, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: shobha.kamath@manipal.edu.
  • Paramasivam G; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: ganesh.p@manipal.edu.
  • Shetty PN; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: dr.prasadnshetty@gmail.com.
  • Singh A; Department of Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: ajitjsingh.mcops@gmail.com.
  • Prakash N S G; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. Electronic address: ganesha.s@learner.manipal.edu.
Indian Heart J ; 76(3): 197-201, 2024.
Article en En | MEDLINE | ID: mdl-38871220
ABSTRACT
This prospective study investigated the association between lipoprotein (a) [Lp(a)] levels and adverse cardiac events in patients undergoing percutaneous coronary intervention (PCI) for coronary artery disease. Among 600 patients, 79.16 % were male. Kaplan Meier analysis revealed significantly higher incidence rates of cardiac death, major adverse cardiac events, myocardial infarction, revascularization and stroke in patients with elevated Lp(a) (≥30 mg/dL). The Cox Regression model identified Lp(a) ≥30 mg/dL as a significant risk factor for adverse events (HR 4.2920; 95%CI 2.58-7.120; p < 0.05). Elevated Lp(a) levels were associated with an increased risk of adverse cardiac events in coronary artery disease patients undergoing PCI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Biomarcadores / Lipoproteína(a) / Intervención Coronaria Percutánea Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Indian Heart J Año: 2024 Tipo del documento: Article Pais de publicación: India
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedad de la Arteria Coronaria / Biomarcadores / Lipoproteína(a) / Intervención Coronaria Percutánea Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Indian Heart J Año: 2024 Tipo del documento: Article Pais de publicación: India