Your browser doesn't support javascript.
loading
Long-term in vivo dissolution of thermo- and pH-responsive, 19F magnetic resonance-traceable and injectable polymer implants.
Jirát-Ziólkowska, Natalia; Vít, Martin; Groborz, Ondrej; Kolouchová, Kristýna; Cervený, David; Sedlácek, Ondrej; Jirák, Daniel.
Afiliación
  • Jirát-Ziólkowska N; Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine Videnska 1958/9 140 21 Prague Czech Republic daniel.jirak@ikem.cz +420-736467349.
  • Vít M; Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University Katerinska 1660/32 Prague 121 08 Czech Republic.
  • Groborz O; Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine Videnska 1958/9 140 21 Prague Czech Republic daniel.jirak@ikem.cz +420-736467349.
  • Kolouchová K; Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University Katerinska 1660/32 Prague 121 08 Czech Republic.
  • Cervený D; Institute of Macromolecular Chemistry, Czech Academy of Sciences Heyrovsky square 2 162 06 Prague Czech Republic.
  • Sedlácek O; Institute of Macromolecular Chemistry, Czech Academy of Sciences Heyrovsky square 2 162 06 Prague Czech Republic.
  • Jirák D; Radiodiagnostic and Interventional Radiology Department, Institute for Clinical and Experimental Medicine Videnska 1958/9 140 21 Prague Czech Republic daniel.jirak@ikem.cz +420-736467349.
Nanoscale Adv ; 6(12): 3041-3051, 2024 Jun 11.
Article en En | MEDLINE | ID: mdl-38868824
ABSTRACT
19F magnetic resonance (19F MR) tracers stand out for their wide range of applications in experimental and clinical medicine, as they can be precisely located in living tissues with negligible fluorine background. This contribution demonstrates the long-term dissolution of multiresponsive fluorinated implants designed for prolonged release. Implants were detected for 14 (intramuscular injection) and 20 (subcutaneous injection) months by 19F MR at 4.7 T, showing favorable MR relaxation times, biochemical stability, biological compatibility and slow, long-term dissolution. Thus, polymeric implants may become a platform for long-term local theranostics.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanoscale Adv Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanoscale Adv Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido