Stereochemical Assignment of the 36-Membered Macrolide Ring Portion of Poecillastrin C.

Irie, Raku; Hitora, Yuki; Watanabe, Ryuichi; Clark, Hugh; Suyama, Yu; Sekiya, Shinji; Suzuki, Toshiyuki; Takada, Kentaro; Matsunaga, Shigeki; Hosokawa, Seijiro; Oikawa, Masato

Irie, Raku; Hitora, Yuki; Watanabe, Ryuichi; Clark, Hugh; Suyama, Yu; Sekiya, Shinji; Suzuki, Toshiyuki; Takada, Kentaro; Matsunaga, Shigeki; Hosokawa, Seijiro; Oikawa, Masato.

Afiliación

Irie R; Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Hitora Y; Yokohama City University, Seto 22-2, Kanazawa-ku, Yokohama 236-0027, Japan.
Watanabe R; Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Clark H; Fisheries Technology Institute, Japan Fisheries Research and Education Agency, 2-12-4 Fukuura, Kanazawa-ku, Yokohama 236-8648, Japan.
Suyama Y; Department of Applied Chemistry, Faculty of Advanced Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Sekiya S; Department of Applied Chemistry, Faculty of Advanced Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Suzuki T; Department of Applied Chemistry, Faculty of Advanced Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.
Takada K; Fisheries Technology Institute, Japan Fisheries Research and Education Agency, 2-12-4 Fukuura, Kanazawa-ku, Yokohama 236-8648, Japan.
Matsunaga S; Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Hosokawa S; Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Oikawa M; Department of Applied Chemistry, Faculty of Advanced Science and Engineering, Waseda University, 3-4-1 Ohkubo, Shinjuku-ku, Tokyo 169-8555, Japan.

Org Lett ; 26(25): 5290-5294, 2024 Jun 28.

Article en En | MEDLINE | ID: mdl-38864719

ABSTRACT

ABSTRACT

Absolute configuration at 12 stereocenters in the 36-membered macrocyclic ring portion of poecillastrin C (1) was disclosed by chemical degradation and NMR analyses of 1, chemical synthesis, and molecular modeling techniques.

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

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