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Bioactive injectable mucoadhesive thermosensitive natural polymeric hydrogels for oral bone and periodontal regeneration.
El-Nablaway, Mohammad; Rashed, Fatema; Taher, Ehab S; Atia, Gamal A; Foda, Tarek; Mohammed, Nourelhuda A; Abdeen, Ahmed; Abdo, Mohamed; Hînda, Ioana; Imbrea, Ana-Maria; Taymour, Noha; Ibrahim, Ateya M; Atwa, Ahmed M; Ibrahim, Samah F; Ramadan, Mahmoud M; Dinu, Stefania.
Afiliación
  • El-Nablaway M; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Rashed F; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.
  • Taher ES; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
  • Atia GA; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.
  • Foda T; Department of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
  • Mohammed NA; Oral Health Sciences Department, Temple University's Kornberg School of Dentistry, Philadelphia, PA, United States.
  • Abdeen A; Physiology and Biochemistry Department, Faculty of Medicine, Mutah University, Al Karak, Jordan.
  • Abdo M; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt.
  • Hînda I; Department of Animal Histology and Anatomy, School of Veterinary Medicine, Badr University in Cairo (BUC), Cairo, Egypt.
  • Imbrea AM; Department of Biology, Faculty of Agriculture, University of Life Sciences "King Michael I" from Timișoara, Timișoara, Romania.
  • Taymour N; Department of Biotechnology, Faculty of Bioengineering of Animal Resources, University of Life Sciences "King Mihai I" from Timisoara, Timișoara, Romania.
  • Ibrahim AM; Department of Substitutive Dental Sciences, College of Dentistry, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.
  • Atwa AM; Department of Administration and Nursing Education, College of Nursing, Prince Sattam bin Abdulaziz University, Al-Kharj, Saudi Arabia.
  • Ibrahim SF; Department of Family and Community Health Nursing, Faculty of Nursing, Port-Said University, Port Said, Egypt.
  • Ramadan MM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt.
  • Dinu S; Department of Internal Medicine, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Front Bioeng Biotechnol ; 12: 1384326, 2024.
Article en En | MEDLINE | ID: mdl-38863491
ABSTRACT
Periodontitis is an inflammation-related condition, caused by an infectious microbiome and host defense that causes damage to periodontium. The natural processes of the mouth, like saliva production and eating, significantly diminish therapeutic medication residency in the region of periodontal disease. Furthermore, the complexity and diversity of pathological mechanisms make successful periodontitis treatment challenging. As a result, developing enhanced local drug delivery technologies and logical therapy procedures provides the foundation for effective periodontitis treatment. Being biocompatible, biodegradable, and easily administered to the periodontal tissues, hydrogels have sparked substantial an intense curiosity in the discipline of periodontal therapy. The primary objective of hydrogel research has changed in recent years to intelligent thermosensitive hydrogels, that involve local adjustable sol-gel transformations and regulate medication release in reaction to temperature, we present a thorough introduction to the creation and efficient construction of new intelligent thermosensitive hydrogels for periodontal regeneration. We also address cutting-edge smart hydrogel treatment options based on periodontitis pathophysiology. Furthermore, the problems and prospective study objectives are reviewed, with a focus on establishing effective hydrogel delivery methods and prospective clinical applications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Bioeng Biotechnol Año: 2024 Tipo del documento: Article País de afiliación: Egipto Pais de publicación: Suiza