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A decay-modeled compressed sensing reconstruction approach for non-Cartesian hyperpolarized 129Xe MRI.
Plummer, Joseph W; Hussain, Riaz; Bdaiwi, Abdullah S; Soderlund, Stephanie A; Hoyos, Xavier; Lanier, John M; Garrison, William J; Parra-Robles, Juan; Willmering, Matthew M; Niedbalski, Peter J; Cleveland, Zackary I; Walkup, Laura L.
Afiliación
  • Plummer JW; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.
  • Hussain R; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Bdaiwi AS; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Soderlund SA; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.
  • Hoyos X; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Lanier JM; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.
  • Garrison WJ; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Parra-Robles J; Department of Biomedical Engineering, University of Cincinnati, Cincinnati, Ohio, USA.
  • Willmering MM; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Niedbalski PJ; Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Cleveland ZI; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Walkup LL; Center for Pulmonary Imaging Research, Department of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Magn Reson Med ; 92(4): 1363-1375, 2024 Oct.
Article en En | MEDLINE | ID: mdl-38860514
ABSTRACT

PURPOSE:

Hyperpolarized 129Xe MRI benefits from non-Cartesian acquisitions that sample k-space efficiently and rapidly. However, their reconstructions are complex and burdened by decay processes unique to hyperpolarized gas. Currently used gridded reconstructions are prone to artifacts caused by magnetization decay and are ill-suited for undersampling. We present a compressed sensing (CS) reconstruction approach that incorporates magnetization decay in the forward model, thereby producing images with increased sharpness and contrast, even in undersampled data.

METHODS:

Radio-frequency, T1, and T 2 * $$ {\mathrm{T}}_2^{\ast } $$ decay processes were incorporated into the forward model and solved using iterative methods including CS. The decay-modeled reconstruction was validated in simulations and then tested in 2D/3D-spiral ventilation and 3D-radial gas-exchange MRI. Quantitative metrics including apparent-SNR and sharpness were compared between gridded, CS, and twofold undersampled CS reconstructions. Observations were validated in gas-exchange data collected from 15 healthy and 25 post-hematopoietic-stem-cell-transplant participants.

RESULTS:

CS reconstructions in simulations yielded images with threefold increases in accuracy. CS increased sharpness and contrast for ventilation in vivo imaging and showed greater accuracy for undersampled acquisitions. CS improved gas-exchange imaging, particularly in the dissolved-phase where apparent-SNR improved, and structure was made discernable. Finally, CS showed repeatability in important global gas-exchange metrics including median dissolved-gas signal ratio and median angle between real/imaginary components.

CONCLUSION:

A non-Cartesian CS reconstruction approach that incorporates hyperpolarized 129Xe decay processes is presented. This approach enables improved image sharpness, contrast, and overall image quality in addition to up-to threefold undersampling. This contribution benefits all hyperpolarized gas MRI through improved accuracy and decreased scan durations.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isótopos de Xenón / Algoritmos / Simulación por Computador / Procesamiento de Imagen Asistido por Computador / Imagen por Resonancia Magnética Límite: Adult / Female / Humans / Male Idioma: En Revista: Magn Reson Med Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Isótopos de Xenón / Algoritmos / Simulación por Computador / Procesamiento de Imagen Asistido por Computador / Imagen por Resonancia Magnética Límite: Adult / Female / Humans / Male Idioma: En Revista: Magn Reson Med Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos