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Diagnostic differences in high-resolution esophageal motility in a large Mexican cohort based on geographic distribution.
Vázquez-Elizondo, Genaro; Remes-Troche, José María; Valdovinos-Díaz, Miguel Ángel; Coss-Adame, Enrique; Morán, Edgardo Suárez; Achem, Sami R.
Afiliación
  • Vázquez-Elizondo G; Gastroenterology Department, Centro de Enfermedades Digestivas ONCARE, Monterrrey, Nuevo León, Mexico.
  • Remes-Troche JM; Gastroenterology Department, Laboratorio de Motilidad Gastrointestinal y Fisiología Digestiva, Instituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz, México.
  • Valdovinos-Díaz MÁ; Gastroenterology Department, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, México.
  • Coss-Adame E; Gastroenterology Department, Instituto Nacional de Ciencias Médicas y Nutrición, Mexico City, México.
  • Morán ES; Gastroenterology Department, Hospital Español, Mexico City, México.
  • Achem SR; Gastroenterology Department, Mayo College of Medicine, Mayo Clinic, Florida, USA.
Dis Esophagus ; 37(10)2024 Oct 02.
Article en En | MEDLINE | ID: mdl-38857460
ABSTRACT
High-resolution esophageal manometry [HRM] has become the gold standard for the evaluation of esophageal motility disorders. It is unclear whether there are HRM differences in diagnostic outcome based on regional or geographic distribution. The diagnostic outcome of HRM in a diverse geographical population of Mexico was compared and determined if there is variability in diagnostic results among referral centers. Consecutive patients referred for HRM during 2016-2020 were included. Four major referral centers in Mexico participated in the study northeastern, southeastern, and central (Mexico City, two centers). All studies were interpreted by experienced investigators using Chicago Classification 3 and the same technology. A total of 2293 consecutive patients were included. More abnormal studies were found in the center (61.3%) versus south (45.8%) or north (45.2%) P < 0.001. Higher prevalence of achalasia was noted in the south (21.5%) versus center (12.4%) versus north (9.5%) P < 0.001. Hypercontractile disorders were more common in the north (11.0%) versus the south (5.2%) or the center (3.6%) P.001. A higher frequency of weak peristalsis occurred in the center (76.8%) versus the north (74.2%) or the south (69.2%) P < 0.033. Gastroesophageal junction obstruction was diagnosed in (7.2%) in the center versus the (5.3%) in the north and (4.2%) in the south p.141 (ns). This is the first study to address the diagnostic outcome of HRM in diverse geographical regions of Mexico. We identified several significant diagnostic differences across geographical centers. Our study provides the basis for further analysis of the causes contributing to these differences.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de la Motilidad Esofágica / Manometría Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Mexico Idioma: En Revista: Dis Esophagus Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Trastornos de la Motilidad Esofágica / Manometría Límite: Adult / Aged / Female / Humans / Male / Middle aged País/Región como asunto: Mexico Idioma: En Revista: Dis Esophagus Asunto de la revista: GASTROENTEROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: México Pais de publicación: Estados Unidos