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Viscoelastic blood coagulation testing system enabled by a non-contact triboelectric angle sensor.
Wang, Baocheng; Wei, Xuelian; Zhou, Hanlin; Cao, Xiaole; Zhang, Enyang; Wang, Zhong Lin; Wu, Zhiyi.
Afiliación
  • Wang B; Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing China.
  • Wei X; School of Nanoscience and Technology University of Chinese Academy of Sciences Beijing China.
  • Zhou H; Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing China.
  • Cao X; School of Nanoscience and Technology University of Chinese Academy of Sciences Beijing China.
  • Zhang E; Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing China.
  • Wang ZL; Beijing Institute of Nanoenergy and Nanosystems Chinese Academy of Sciences Beijing China.
  • Wu Z; School of Nanoscience and Technology University of Chinese Academy of Sciences Beijing China.
Exploration (Beijing) ; 4(1): 20230073, 2024 Feb.
Article en En | MEDLINE | ID: mdl-38854489
ABSTRACT
Thromboelastography (TEG) remains a convenient and effective viscoelastic blood coagulation testing device for guiding blood component transfusion and assessing the risk of thrombosis. Here, a TEG enabled by a non-contact triboelectric angle sensor (NTAS) with a small size (∼7 cm3) is developed for assessing the blood coagulation system. With the assistance of a superelastic torsion wire structure, the NTAS-TEG realizes the detection of blood viscoelasticity. Benefiting from a grating and convex design, the NTAS holds a collection of compelling features, including accurate detection of rotation angles from -2.5° to 2.5°, high linearity (R 2 = 0.999), and a resolution of 0.01°. Besides, the NTAS exhibits merits of low cost and simplified fabrication. Based on the NTAS-TEG, a viscoelastic blood coagulation detection and analysis system is successfully constructed, which can provide a graph and parameters associated with clot initiation, formation, and stability for clinicians by using 0.36 mL of whole blood. The system not only validates the feasibility of the triboelectric coagulation testing sensor, but also further expands the application of triboelectric sensors in healthcare.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Exploration (Beijing) Año: 2024 Tipo del documento: Article Pais de publicación: China

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Exploration (Beijing) Año: 2024 Tipo del documento: Article Pais de publicación: China