Your browser doesn't support javascript.
loading
Characterization, hazard identification, and risk assessment of volatile organic compounds in Poly(butylene adipate-co-terephthalate)-based food contact articles.
Li, Hanke; Miao, Hongjian; Chen, Lichang; Su, Qi-Zhi; Liu, Zhenwei; Xie, Canghao; Liang, Jinxin; Wu, Siliang; Cui, An-Qi; Xu, Can; Dong, Ben; Li, Dan; Chen, Sheng; Zhong, Huai-Ning; Zheng, Jianguo.
Afiliación
  • Li H; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China. Electronic address: lihk@iqtc-fcm.com.
  • Miao H; NHC Key Laboratory of Food Safety Risk Assessment, China National Center for Food Safety Risk Assessment, Beijing, 100021, China.
  • Chen L; Department of Medical Statistics, School of Public Health, Sun Yat-sen University, Guangzhou, 510080, China.
  • Su QZ; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou, 510641, China.
  • Liu Z; Ningbo Homelink Eco-iTech Co., Ltd., Ningbo, 315207, China.
  • Xie C; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Liang J; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Wu S; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Cui AQ; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Xu C; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou, 510641, China.
  • Dong B; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Li D; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Chen S; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
  • Zhong HN; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China; State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou, 510641, China.
  • Zheng J; National Reference Laboratory for Food Contact Material (Guangdong), Guangzhou Customs Technology Center, Guangzhou, 510075, China.
Food Chem Toxicol ; 190: 114808, 2024 Aug.
Article en En | MEDLINE | ID: mdl-38852758
ABSTRACT
The chemical safety of poly (butylene adipate-co-terephthalate) (PBAT) based food contact articles (FCAs) has aroused increasing toxicological concerns in recent years, but the chemical characterization and associated risk assessment still remain inadequate as it fails to elucidate the distribution pattern and discern the potential genotoxic and carcinogenic hazards of the identified substances. Herein, the volatile organic compounds (VOCs) in 50 batches of PBAT-based FCAs of representative categories and 10 batches of PLA and PBAT pellets were characterized, by which 237 VOCs of 10 chemical categories were identified and exhibited characteristic distribution patterns in the chemical spaces derived from their molecular descriptors. Chemical hazards associated with the identified VOCs were discerned by a hazard-driven classification scheme integrating hazard-related knowledge from multiple publicly available sources, and 34 VOCs were found to bear genotoxic or carcinogenic hazards and to feature higher average molecular weight than the other VOCs. Finally, the Risk and hazard quotient (HQ) calculated as the metrics of risk suggested that all identified VOCs posed acceptable risks (Risk<10-4 or HQ < 1), whereas oxolane, butyrolactone, N,N-dimethylacetamide, 2-butoxyethanol, benzyl alcohol, and 1,2,3-trichloropropane posed non-negligible (Risk>10-6) genotoxic or carcinogenic risk and thus should be of prioritized concern to promote the chemical safety of PBAT-based FCAs.
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliésteres / Embalaje de Alimentos / Compuestos Orgánicos Volátiles Límite: Humans Idioma: En Revista: Food Chem Toxicol Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Poliésteres / Embalaje de Alimentos / Compuestos Orgánicos Volátiles Límite: Humans Idioma: En Revista: Food Chem Toxicol Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido