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Orbital cavernous venous malformation shrinkage during fractionated stereotactic radiotherapy contributing to the development of radiation retinopathy.
Hughes, Laura; Cohn, Amy C; Haghighi, Neda; McNab, Alan A.
Afiliación
  • Hughes L; Orbital, Plastics and Lacrimal Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.
  • Cohn AC; Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia.
  • Haghighi N; Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia.
  • McNab AA; Medical Retina Unit, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.
Eur J Ophthalmol ; 34(5): NP53-NP58, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38847131
ABSTRACT

BACKGROUND:

Posterior movement of ocular tissue secondary to orbital cavernous venous malformation shrinkage from fractionated stereotactic radiotherapy can allow healthy structures to move into the radiation field during treatment. This may carry an increased risk of radiation-induced retinopathy.

METHODS:

We present a case of a young female whose radiotherapy treatment for an orbital cavernous venous malformation resulted in a 3 mm reduction in proptosis and subsequent retinopathy.

RESULTS:

The severity of the patient's radiation-induced radiotherapy exceeded expectations. The venous malformation shrinkage during treatment and ensuing posterior movement of the globe suggested an increased involvement of ocular tissue in the radiation field, prompting consideration of interval neuroimaging and tumour mapping.

CONCLUSIONS:

We describe and suggest a protocol of onboard neuroimaging during the radiation therapy course to better target tumour volumes and minimise collateral tissue damage. To our knowledge, this has not been previously described in the ophthalmic literature.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos por Radiación / Enfermedades de la Retina / Imagen por Resonancia Magnética / Radiocirugia Límite: Adult / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Traumatismos por Radiación / Enfermedades de la Retina / Imagen por Resonancia Magnética / Radiocirugia Límite: Adult / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Australia Pais de publicación: Estados Unidos