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Kikuchi disease complicated with aseptic meningitis following COVID-19 Vaccination: a case report.
Kularathna, Manana Dewage Sankani Vishvara; Medagama, Arjuna; Bandara, Ruwanthi; Yasarathna, Duminda; Dilani, Madugeta Kumarage Ishara; Anuththara, Thushani.
Afiliación
  • Kularathna MDSV; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka. vishvarakularathna@gmail.com.
  • Medagama A; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka.
  • Bandara R; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka.
  • Yasarathna D; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka.
  • Dilani MKI; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka.
  • Anuththara T; Teaching Hospital Peradeniya, Peradeniya, Kandy, Sri Lanka.
J Med Case Rep ; 18(1): 270, 2024 Jun 06.
Article en En | MEDLINE | ID: mdl-38840233
ABSTRACT

BACKGROUND:

Kikuchi Fujimoto disease is a rare self-limiting disorder mainly affecting young Asian females. The typical presentation is unexplained fever with associated cervical lymphadenopathy. It can mimic many sinister diseases such as lymphoma, tuberculosis, and systemic lupus erythematosus. Aseptic meningitis due to Kikuchi disease is extremely rare, and majority were reported from Japan. There have been no published cases of aseptic meningitis due to Kikuchi disease in Sri Lanka. CASE PRESENTATION A 29 years old Sri Lankan female presented with a prolonged fever for three weeks with an associated headache for five days duration. She developed painful cervical lymphadenopathy during the hospital stay. She has been previously well and had been vaccinated against COVID-19 six weeks before. Her lumbar puncture showed lymphocytic pleocytosis with marginally elevated protein levels and reduced ratio of serum to CSF sugar. Lymph node biopsy was consistent with necrotizing lymphadenitis. She was subsequently diagnosed with Kikuchi disease complicated with aseptic meningitis. She responded to corticosteroids well and had an uneventful recovery.

CONCLUSION:

Kikuchi disease is a rare self-limiting disorder that can be complicated with aseptic meningitis on infrequent occasions. Other conditions such as tuberculosis, lymphoma, systemic lupus erythematosus, and adult-onset Still's disease should be considered as differential diagnoses. Knowledge of Kikuchi disease and its complications will prevent unnecessary investigations which delay the early diagnosis and treatment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfadenitis Necrotizante Histiocítica / Meningitis Aséptica Límite: Adult / Female / Humans País/Región como asunto: Asia Idioma: En Revista: J Med Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Sri Lanka Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfadenitis Necrotizante Histiocítica / Meningitis Aséptica Límite: Adult / Female / Humans País/Región como asunto: Asia Idioma: En Revista: J Med Case Rep Año: 2024 Tipo del documento: Article País de afiliación: Sri Lanka Pais de publicación: Reino Unido