A fluorescent probe based on cyclochalcone for detecting peroxynitrite.

Liu, Li-Hao; Shang, Xian-Zhao; Yuan, Jian-Hao; Luo, Yi-Ning; Wang, Jia-Yi; Xue, Xiao-Lei; Jiang, Nan; Wang, Kun-Peng; Hu, Zhi-Qiang

Liu, Li-Hao; Shang, Xian-Zhao; Yuan, Jian-Hao; Luo, Yi-Ning; Wang, Jia-Yi; Xue, Xiao-Lei; Jiang, Nan; Wang, Kun-Peng; Hu, Zhi-Qiang.

Afiliación

Liu LH; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Shang XZ; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Yuan JH; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Luo YN; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Wang JY; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Xue XL; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China. xuexiaolei@qust.edu.cn.
Jiang N; Genetic Testing Center, Women and Children's Hospital Affiliated to Qingdao University, Qingdao, 266034, Shandong, China. sdqd_jn@163.com.
Wang KP; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China. wangkunpeng@qust.edu.cn.
Hu ZQ; Key Laboratory of Optic-Electric Sensing and Analytical Chemistry for Life Science, MOE, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.

Photochem Photobiol Sci ; 23(6): 1031-1039, 2024 Jun.

Article en En | MEDLINE | ID: mdl-38839721

ABSTRACT

ABSTRACT

A novel cyclic chalcone fluorescent probe C-PN was synthesized to detect ONOO-. After reaction with peroxynitrite, the double bond of C-PN in the cyclic chalcone structure was disconnected, which caused the change of intramolecular charge transfer (ICT) effect, emitting blue fluorescence and quenching orange red fluorescence. Visible to the naked eye, the color of the probe solution changed. The probe showed low sensitivity (detection limit = 20.2 nm), short response time (less than 60 s) at low concentration of ONOO-, good visibility, and good selectivity and stability for ONOO-.

Palabras clave

Chalcone; Fluorescent probe; Peroxynitrite

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Photochem Photobiol Sci Asunto de la revista: BIOLOGIA / QUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido

Texto completo

Añadir a Mi BVS

Imprimir

XML

PubMed Links

Buscar en Google