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Quality of Life Outcomes for Parotid Malignancies.
Tang, Anthony; Li, Jinhong; Scheff, Nicole; Johnson, Jonas T; Contrera, Kevin J; Nilsen, Marci L.
Afiliación
  • Tang A; University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, U.S.A.
  • Li J; Department of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, U.S.A.
  • Scheff N; Department of Neurobiology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
  • Johnson JT; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
  • Contrera KJ; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
  • Nilsen ML; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, U.S.A.
Laryngoscope ; 2024 Jun 04.
Article en En | MEDLINE | ID: mdl-38837232
ABSTRACT

BACKGROUND:

This study describes patient-reported outcome measures (PROMs) and associated factors in patients who underwent surgery for malignant parotid tumors (MPT).

METHODS:

This is a retrospective study of all surgically treated MPT patients in a multidisciplinary head and neck cancer (HNC) survivorship clinic (2017-2023). PROMs included University of Washington Quality of Life Questionnaire (UW-QOL), Eating Assessment Tool (EAT-10), Patient Health Questionnaire (PHQ-8), Generalized Anxiety Disorder (GAD-7), Neck Disability Index (NDI), and Insomnia Severity Index. Multivariable regression analysis was used to investigate clinical predictors associated with PROMs.

RESULTS:

In 62 MPT patients, the prevalence of clinically relevant dysphagia symptoms (EAT-10), elevated symptoms of depression (PHQ-8), moderate/severe symptoms of anxiety (GAD-7), moderate/severe neck pain with activities of daily living (NDI), and moderate/severe symptoms of insomnia at last follow-up was 32.3%, 15.5%, 7.1%, 17.7%, and 7.2%, respectively. Nonparametric one-sided test revealed that patients treated with adjuvant CRT had significantly worse physical QOL, social-emotional QOL, and swallowing scores than patients treated with surgery alone (p = 0.01, p = 0.02, p = 0.03, respectively); that patients treated with surgery and adjuvant RT had significantly worse physical QOL and social-emotional QOL than patients treated with surgery alone (p < 0.01, p = 0.01, respectively) and that patients treated with surgery and adjuvant CRT had significantly worse swallowing and neck pain than patients treated with surgery and adjuvant RT (p = 0.03, p = 0.05, respectively).

CONCLUSIONS:

In patients with surgically treated MPT, adjuvant CRT and RT were associated with worse PROMs. LEVEL OF EVIDENCE 4 Laryngoscope, 2024.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Laryngoscope Asunto de la revista: OTORRINOLARINGOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos