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Physical exercise in liver diseases.
Zhang, Yunwei; Cao, Chunyan; Li, Chaofan; Witt, Russell G; Huang, Hai; Tsung, Allan; Zhang, Hongji.
Afiliación
  • Zhang Y; Department of Surgery, University of Virginia, Charlottesville, Virginia, USA.
  • Cao C; Department of Surgery, University of Virginia, Charlottesville, Virginia, USA.
  • Li C; Department of Medicine, Beirne B. Carter Center for Immunology Research, University of Virginia, Charlottesville, Virginia, USA.
  • Witt RG; Division of Infectious Disease and International Health, Department of Medicine, University of Virginia, Charlottesville, Virginia, USA.
  • Huang H; Department of Surgery, University of Virginia, Charlottesville, Virginia, USA.
  • Tsung A; Division of Hepatology, Center for Immunology and Inflammation, Departments of Molecular Medicine, Medicine, and Surgery at the School of Medicine, Feinstein Institutes for Medical Research, Manhasset, New York, USA.
  • Zhang H; Department of Surgery, University of Virginia, Charlottesville, Virginia, USA.
Hepatology ; 2024 Jun 05.
Article en En | MEDLINE | ID: mdl-38836646
ABSTRACT
Liver diseases contribute to ~2 million deaths each year and account for 4% of all deaths globally. Despite various treatment options, the management of liver diseases remains challenging. Physical exercise is a promising nonpharmacological approach to maintain and restore homeostasis and effectively prevent and mitigate liver diseases. In this review, we delve into the mechanisms of physical exercise in preventing and treating liver diseases, highlighting its effects on improving insulin sensitivity, regulating lipid homeostasis, and modulating immune function. In addition, we evaluate the impact of physical exercise on various liver diseases, including liver ischemia/reperfusion injury, cardiogenic liver disease, metabolic dysfunction-associated steatotic liver disease, portal hypertension, cirrhosis, and liver cancer. In conclusion, the review underscores the effectiveness of physical exercise as a beneficial intervention in combating liver diseases.

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Hepatology Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Hepatology Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos