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Retrospective operationalization of allostatic load in patients with cancer: A systematic review.
McQuitty, Emelie N; Black, T Austin; Rousseau, Morgan A; Parvathaneni, Aarthi; Gonna, Nadeen; Farris, David P; Nelson, Kelly C.
Afiliación
  • McQuitty EN; John P. and Kathrine G. McGovern Medical School at UTHealth Houston, Houston, TX, USA.
  • Black TA; John P. and Kathrine G. McGovern Medical School at UTHealth Houston, Houston, TX, USA.
  • Rousseau MA; John P. and Kathrine G. McGovern Medical School at UTHealth Houston, Houston, TX, USA.
  • Parvathaneni A; John P. and Kathrine G. McGovern Medical School at UTHealth Houston, Houston, TX, USA.
  • Gonna N; John P. and Kathrine G. McGovern Medical School at UTHealth Houston, Houston, TX, USA.
  • Farris DP; Research Medical Library, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Nelson KC; Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: kcnelson1@mdanderson.org.
Psychoneuroendocrinology ; 167: 107085, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38833997
ABSTRACT
Allostatic load (AL) has been shown to impact cancer outcomes. At present, no gold standard exists surrounding AL computation. As such, a systematic review of the literature was performed to identify studies that retrospectively calculated AL in patients with cancer. The following variables were collected for each study AL calculation method, including the biomarkers used and their cutoff values, number of biosystems represented, definition of high AL, and the use of proxy biomarkers. Thirteen articles were included for full-text review. The number of biomarkers used in the calculation of AL varied considerably, ranging from 6 to 16. Considerable variability was also observed in terms of utilized biomarkers and biosystem representation. This lack of standardization complicates retrospective AL calculation among patients with cancer. Nonetheless, determining AL in patients with cancer presents an important step in the optimization of patient care and outcomes.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alostasis / Neoplasias Límite: Humans Idioma: En Revista: Psychoneuroendocrinology Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Alostasis / Neoplasias Límite: Humans Idioma: En Revista: Psychoneuroendocrinology Año: 2024 Tipo del documento: Article Pais de publicación: Reino Unido