Your browser doesn't support javascript.
loading
Copper-Catalyzed Directed Hydroindolation/Annulation Sequence of Alkynes with Indoles via Copper Carbenes.
Ma, Guang; Cui, Qiu-Yue; Wei, Kua-Fei; Jiang, Xiao-Lei; Lv, Dong-Can; Xue, Xiaoping; Zhu, Xiu-Hong; Ru, Guang-Xin; Xie, Xinfeng; Shen, Wen-Bo.
Afiliación
  • Ma G; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Cui QY; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Wei KF; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Jiang XL; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Lv DC; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Xue X; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Zhu XH; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Ru GX; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
  • Xie X; College of Forest Resources and Environmental Science, Michigan Technological University, Houghton, Michigan 49931-1295, United States.
  • Shen WB; College of Sciences and College of Forestry, Henan Agricultural University, Zhengzhou 450002, China.
Org Lett ; 26(23): 4945-4952, 2024 Jun 14.
Article en En | MEDLINE | ID: mdl-38832831
ABSTRACT
Described herein is an efficient copper-catalyzed tandem alkyne indolylcupration-initiated 1,2-indole migration/6π-electrocyclic reaction of allene-ynamides with indoles by the in situ-generated metal carbenes. This method allows the efficient synthesis of valuable indole-fused spirobenzo[f]indole-cyclohexanes with high regio- and stereoselectivity. In addition, this reaction affords rapid access to the functionalized spirobenzo[f]indole-cyclohexanes in the absence of indoles by a presumable 5-exo-dig cyclization/Friedel-Crafts alkylation via copper-containing all-carbon 1,4-dipoles.
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos