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The Prognostic Value of the Triglyceride-Glucose Index in Forecasting Ten-Year Major Adverse Cardiovascular Events in Non-Diabetic Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention.
Köktürk, Ugur; Onalan, Orhan; Somuncu, Mustafa Umut; Uygur, Begüm; Erbay, Ilke; Çakan, Fahri; Avci, Ahmet.
Afiliación
  • Köktürk U; Department of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Türkiye.
  • Onalan O; Department of Cardiology, Karabuk University Training and Research Hospital, Karabuk, Türkiye.
  • Somuncu MU; Department of Cardiology, Faculty of Medicine, Aydin Adnan Menderes University, Aydin, Türkiye.
  • Uygur B; Department of Cardiology, University of Health Sciences, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Türkiye.
  • Erbay I; Department of Cardiology, Karabuk University Training and Research Hospital, Karabuk, Türkiye.
  • Çakan F; Department of Cardiology, Cerkezkoy State Hospital, Tekirdag, Türkiye.
  • Avci A; Department of Cardiology, Faculty of Medicine, Zonguldak Bülent Ecevit University, Zonguldak, Türkiye.
Turk Kardiyol Dern Ars ; 52(4): 253-259, 2024 Jun.
Article en En | MEDLINE | ID: mdl-38829642
ABSTRACT

OBJECTIVE:

This study aimed to explore the association between the triglyceride-glucose (TyG) index and major adverse cardiovascular events (MACE) over a ten-year period in non-diabetic patients with acute myocardial infarction (MI) undergoing primary percutaneous coronary intervention (PCI).

METHODS:

We included 375 consecutive non-diabetic patients presenting with acute MI who underwent primary PCI. The TyG index was calculated and patients were divided based on a cut-off value of ≥ 8.84 into high and low TyG index groups. The incidence of MACE, including all-cause mortality, target vessel revascularization, reinfarction, and rehospitalization for heart failure, was assessed over 10 years.

RESULTS:

Over the next 10 years, patients who underwent PCI for acute MI experienced a significantly higher incidence of MACE in the group with a high TyG index (≥ 8.84) (P = 0.004). Multivariable analysis revealed that the TyG index independently predicted MACE in these patients [odds ratio = 1.64; 95% confidence interval (CI) 1.22-2.21; P = 0.002]. Analysis of the receiver operating characteristic curve indicated that the TyG index effectively predicted MACE in patients with acute MI following PCI, with an area under the curve of 0.562 (95% CI 0.503-0.621; P = 0.038).

CONCLUSION:

This study established a correlation between high TyG index levels and an elevated risk of MACE in non-diabetic patients with acute MI. The findings suggest that the TyG index could be a reliable indicator of clinical outcomes for non-diabetic acute MI patients undergoing PCI.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Glucemia / Intervención Coronaria Percutánea / Infarto del Miocardio Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Turk Kardiyol Dern Ars Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Turquía
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Triglicéridos / Glucemia / Intervención Coronaria Percutánea / Infarto del Miocardio Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Turk Kardiyol Dern Ars Asunto de la revista: CARDIOLOGIA Año: 2024 Tipo del documento: Article Pais de publicación: Turquía