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Squamous cell carcinoma and Crohn's disease: a sometimes-challenging diagnosis.
Boudabbous, Mona; Barkia, Baha; Feki, Wiem; Gdoura, Héla; Chtourou, Lassad; Moalla, Manel; Mnif, Leila; Amouri, Ali; Mnif, Zeinab; Tahri, Nabil.
Afiliación
  • Boudabbous M; Gastroenterology Department, Hédi Chaker Hospital, Sfax, 3000, Tunisia.
  • Barkia B; Medecin Sfax University, Sfax university, 3000, Tunisia.
  • Feki W; Gastroenterology Department, Hédi Chaker Hospital, Sfax, 3000, Tunisia.
  • Gdoura H; Medecin Sfax University, Sfax university, 3000, Tunisia.
  • Chtourou L; Radiology Department, Hédi Chaker Hospital, Sfax, 3000, Tunisia.
  • Moalla M; Medecin Sfax University, Sfax university, 3000, Tunisia.
  • Mnif L; Gastroenterology Department, Hédi Chaker Hospital, Sfax, 3000, Tunisia.
  • Amouri A; Medecin Sfax University, Sfax university, 3000, Tunisia.
  • Mnif Z; Gastroenterology Department, Hédi Chaker Hospital, Sfax, 3000, Tunisia.
  • Tahri N; Medecin Sfax University, Sfax university, 3000, Tunisia.
Future Sci OA ; 10(1): FSO907, 2024.
Article en En | MEDLINE | ID: mdl-38827804
ABSTRACT

Aim:

Non-melanoma skin cancers are more common in people with inflammatory bowel disease. However, these tumors can rarely mimic a cutaneous manifestation of the disease, which delays diagnosis and clouds prognosis. Observation A 35-year-old man with stenosing and fistulizing ileocolic Crohn's disease developed squamous cell carcinoma mimicking a groin fold abscess. After surgical drainage of the abscess, despite antibiotics and therapy combining azathioprine with infliximab, the abscess has recurred. Biopsies revealed a cutaneous squamous cell carcinoma. Palliative radiotherapy-chemotherapy was initiated, but the patient died after 3 months.

Conclusion:

This observation illustrates the increased risk of non-melanoma skin cancers in inflammatory bowel disease patients, particularly those exposed to thiopurines, and the value of diagnosing them at an early stage.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Future Sci OA Año: 2024 Tipo del documento: Article País de afiliación: Túnez Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Future Sci OA Año: 2024 Tipo del documento: Article País de afiliación: Túnez Pais de publicación: Reino Unido