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Developing the OpenFlexure Microscope towards medical use: technical and social challenges of developing globally accessible hardware for healthcare.
Knapper, Joe; Whiteford, Freya; Rosen, Daniel; Wadsworth, William; Stirling, Julian; Mkindi, Catherine; Mduda, Joram; Sanga, Valerian L; Nyakyi, Paul T; Mboa Nkoudou, Thomas Hervé; Jafsia, Elisée; Fadanka, Stephane; Hummel, Kelsey; Anandasabapathy, Sharmila; Bowman, Richard.
Afiliación
  • Knapper J; University of Glasgow , Glasgow, UK.
  • Whiteford F; University of Glasgow , Glasgow, UK.
  • Rosen D; Baylor College of Medicine , Houston, Texas, USA.
  • Wadsworth W; Department of Physics, University of Bath , Bath, UK.
  • Stirling J; Foxhill Engineering , Bath, UK.
  • Mkindi C; Ifakara Health Institute , Ifakara, Tanzania.
  • Mduda J; Ifakara Health Institute , Ifakara, Tanzania.
  • Sanga VL; Bongo Tech and Research Labs , Dar es Salaam, Tanzania.
  • Nyakyi PT; Bongo Tech and Research Labs , Dar es Salaam, Tanzania.
  • Mboa Nkoudou TH; Mboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
  • Jafsia E; Mboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
  • Fadanka S; Mboalab and African Higher Institute of Open Science and Hardware (AHIOSH) , Yaounde, Cameroon.
  • Hummel K; MD Anderson Cancer Centre , Houston, Texas, USA.
  • Anandasabapathy S; Baylor College of Medicine , Houston, Texas, USA.
  • Bowman R; University of Glasgow , Glasgow, UK.
Philos Trans A Math Phys Eng Sci ; 382(2274): 20230257, 2024 Jul 09.
Article en En | MEDLINE | ID: mdl-38826050
ABSTRACT
The OpenFlexure Microscope is an accessible, three-dimensional-printed robotic microscope, with sufficient image quality to resolve diagnostic features including parasites and cancerous cells. As access to lab-grade microscopes is a major challenge in global healthcare, the OpenFlexure Microscope has been developed to be manufactured, maintained and used in remote environments, supporting point-of-care diagnosis. The steps taken in transforming the hardware and software from an academic prototype towards an accepted medical device include addressing technical and social challenges, and are key for any innovation targeting improved effectiveness in low-resource healthcare. This article is part of the Theo Murphy meeting issue 'Open, reproducible hardware for microscopy'.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Límite: Humans Idioma: En Revista: Philos Trans A Math Phys Eng Sci Asunto de la revista: BIOFISICA / ENGENHARIA BIOMEDICA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microscopía Límite: Humans Idioma: En Revista: Philos Trans A Math Phys Eng Sci Asunto de la revista: BIOFISICA / ENGENHARIA BIOMEDICA Año: 2024 Tipo del documento: Article País de afiliación: Reino Unido Pais de publicación: Reino Unido