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Breast cancer detection based on cancer antigen 15-3; emphasis on optical and electrochemical methods: A review.
Pourmadadi, Mehrab; Ghaemi, Amirhossein; Khanizadeh, Amirhossein; Yazdian, Fatemeh; Mollajavadi, Yasin; Arshad, Rabia; Rahdar, Abbas.
Afiliación
  • Pourmadadi M; Protein Research Center, Shahid Beheshti University, Tehran, GC, 1983963113, Iran.
  • Ghaemi A; Department of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Khanizadeh A; Department of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran.
  • Yazdian F; Department of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran. Electronic address: yazdian@ut.ac.ir.
  • Mollajavadi Y; Department of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran.
  • Arshad R; Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan; Adjunct Professor at Equator University of Science and Technology, Uganda.
  • Rahdar A; Department of Physics, Faculty of Sciences, University of Zabol, Zabol, 538-98615, Iran; Key Laboratory of Modeling and Simulation-based Reliability and Optimization, University of Zabol, Zabol, Iran. Electronic address: a.rahdar@uoz.ac.ir.
Biosens Bioelectron ; 260: 116425, 2024 Sep 15.
Article en En | MEDLINE | ID: mdl-38824703
ABSTRACT
Cancer antigen 15-3 (CA 15-3) is a crucial marker used in the diagnosis and monitoring of breast cancer (BC). The demand for early and precise cancer detection has grown, making the creation of biosensors that are highly sensitive and specific essential. This review paper provides a thorough examination of the progress made in optical and electrochemical biosensors for detecting the cancer biomarker CA 15-3. We focus on explaining their fundamental principles, sensitivity, specificity, and potential for point-of-care applications. The performance attributes of these biosensors are assessed by considering their limits of detection, reaction times, and operational stability, while also making comparisons to conventional methods of CA 15-3 detection. In addition, we explore the incorporation of nanomaterials and innovative transducer components to improve the performance of biosensors. This paper conducts a thorough examination of recent studies to identify the existing obstacles. It also suggests potential areas for future research in this fast progressing field.The paper provides insights into their advancement and utilization to enhance patient outcomes. Both categories of biosensors provide significant promise for the detection of CA 15-3 and offer distinct advantages compared to conventional analytical approaches.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Técnicas Biosensibles / Biomarcadores de Tumor / Mucina-1 / Técnicas Electroquímicas Límite: Female / Humans Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Técnicas Biosensibles / Biomarcadores de Tumor / Mucina-1 / Técnicas Electroquímicas Límite: Female / Humans Idioma: En Revista: Biosens Bioelectron Asunto de la revista: BIOTECNOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Irán Pais de publicación: Reino Unido