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Real-world assessment of multipolar and point-by-point mapping for premature ventricular contraction ablation.
Sousa, Pedro A; Tonko, Johanna; Dilling-Boer, Dagmara; Barra, Sérgio; Eberl, Anna-Sophie; Pezo, Borka; Cortez-Dias, Nuno; Khoueiry, Ziad; Medeiros, Paulo; Rodríguez-Mañero, Moisés; Lebreiro, Ana; Pereira, Mariana; Puga, Luís; Scherr, Daniel; António, Natália; Ferreira, Afonso; Saleiro, Carolina; Lagrange, Philippe; Adão, Luis; de Sousa, Joao; Elvas, Luís; Oliveira, Mário; Gonçalves, Lino; Silberbauer, John.
Afiliación
  • Sousa PA; Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Morada: Praceta Prof Mota Pinto, 3000-075 Coimbra, Portugal.
  • Tonko J; Cardiology Department, Sussex Cardiac Centre, Brighton, UK.
  • Dilling-Boer D; Institute of Cardiovascular Science, University College London, London, UK.
  • Barra S; Cardiology Department, Hartcentrum Hasselt, Hasselt, Belgium.
  • Eberl AS; Cardiology Department, Hospital da Luz Arrábida, V. N. Gaia, Portugal.
  • Pezo B; Division of Cardiology, Department of Medicine, Medical University of Graz, Graz, Austria.
  • Cortez-Dias N; Cardiology Department, University Hospital Centre Zagreb, Zagreb, Croatia.
  • Khoueiry Z; Arrhythmia Unit, Cardiology Department, Santa Maria University Hospital, Lisbon Academic Medical Center, Lisbon, Portugal.
  • Medeiros P; Cardiology Department, Clinique Saint Pierre, Perpignan, France.
  • Rodríguez-Mañero M; Cardiology Department, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, Portugal.
  • Lebreiro A; Cardiology Department, University Center Hospital of Santiago, Santiago de Compostela, Spain.
  • Pereira M; Cardiology Department, University Hospital Center of São João, Porto, Portugal.
  • Puga L; Biosense Webster, Portugal.
  • Scherr D; Cardiology Department, Centro Hospitalar de Entre Douro e Vouga, Santa Maria da Feira, Portugal.
  • António N; Division of Cardiology, Department of Medicine, Medical University of Graz, Graz, Austria.
  • Ferreira A; Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Morada: Praceta Prof Mota Pinto, 3000-075 Coimbra, Portugal.
  • Saleiro C; Faculty of Medicine, ICBR, University of Coimbra, Coimbra, Portugal.
  • Lagrange P; Cardiology Department, Santa Marta Hospital, Lisboa, Portugal.
  • Adão L; Arrhythmia Unit, Cardiology Department, Santa Maria University Hospital, Lisbon Academic Medical Center, Lisbon, Portugal.
  • de Sousa J; Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Morada: Praceta Prof Mota Pinto, 3000-075 Coimbra, Portugal.
  • Elvas L; Cardiology Department, Clinique Saint Pierre, Perpignan, France.
  • Oliveira M; Cardiology Department, University Hospital Center of São João, Porto, Portugal.
  • Gonçalves L; Arrhythmia Unit, Cardiology Department, Santa Maria University Hospital, Lisbon Academic Medical Center, Lisbon, Portugal.
  • Silberbauer J; Pacing & Electrophysiology Unit, Cardiology Department, Coimbra's Hospital and University Center, Morada: Praceta Prof Mota Pinto, 3000-075 Coimbra, Portugal.
Europace ; 26(6)2024 Jun 03.
Article en En | MEDLINE | ID: mdl-38818846
ABSTRACT

AIMS:

We aimed to assess the acute and midterm efficacy of premature ventricular contraction (PVC) ablation guided by multielectrode and point-by-point (PbP) mapping. METHODS AND

RESULTS:

This is a retrospective, international multicentre study of consecutive patients referred for PVC ablation in 10 hospital centres from January 2017 to December 2021. Based on the mapping approach, two cohorts were identified the 'Multipolar group', where a dedicated high-density mapping catheter was employed, and the 'PbP group', where mapping was performed with the ablation catheter. Procedural endpoints, safety, and acute (procedural) and midterm efficacies were assessed. Of the 698 patients included in this study, 592 received activation mapping [46% males, median age of 55 (41-65) years]-248 patients in the Multipolar group and 344 patients in the PbP group. A higher number of activation points [432 (217-843) vs. 95 (42-185), P < 0.001], reduced mapping time (40 ± 38 vs. 61 ± 50 min, P < 0.001), and shorter procedure time (124 ± 60 vs. 143 ± 63 min, P < 0.001) were reported in the Multipolar group. Both groups had high acute success rates (84.7% with Multipolar mapping vs. 81.3% with PbP mapping, P = 0.63), as well as midterm efficacy (83.4% vs. 77.4%, P = 0.08), with no significant differences in the risk of adverse events (6.0% vs. 3.5%, P = 0.24). However, for left-sided PVC ablation specifically, there was a higher midterm efficacy in the Multipolar group (80.7% vs. 69.5%, P = 0.04), with multipolar mapping being an independent predictor of success [adjusted OR = 2.231 (95% CI, 1.476-5.108), P = 0.02].

CONCLUSION:

The acute and midterm efficacies of PVC ablation are high with both multipolar and PbP mapping, although the former allows for quicker procedures and may potentially improve the outcomes of left-sided PVC ablation.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ablación por Catéter / Complejos Prematuros Ventriculares Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Europace Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ablación por Catéter / Complejos Prematuros Ventriculares Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Europace Asunto de la revista: CARDIOLOGIA / FISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Portugal Pais de publicación: Reino Unido