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Lung cancer patients with anaplastic lymphoma kinase rearrangement lose affiliation with labor market at diagnosis.
Andersen, Jon Lykkegaard; Johansen, Jakob Sidenius; Urbanska, Edyta Maria; Meldgaard, Peter; Hjorth-Hansen, Peter; Kristiansen, Charlotte; Stelmach, Miroslaw; Santoni-Rugiu, Eric; Ulhøi, Maiken Parm; Højgaard, Betina; Jensen, Morten Sall; Dydensborg, Anders Bondo; Dünweber, Christina; Hansen, Karin Holmskov.
Afiliación
  • Andersen JL; Department of Oncology, Herlev & Gentofte University Hospital, DK-2730, Herlev, Denmark.
  • Johansen JS; Department of Oncology, Herlev & Gentofte University Hospital, DK-2730, Herlev, Denmark.
  • Urbanska EM; Present address: Employment with Dept. of Oncology, Herlev & Gentofte University hospital, DK-2730, Herlev, Denmark, Denmark ended during the writing of the article.
  • Meldgaard P; Department of Oncology, Rigshospitalet, Copenhagen University Hospital, DK-2100, Copenhagen, Denmark.
  • Hjorth-Hansen P; Department of Oncology, Aarhus University Hospital, DK-8000, Aarhus, Denmark.
  • Kristiansen C; Department of Oncology, Aalborg University Hospital, DK-9000, Aalborg, Denmark.
  • Stelmach M; Department of Oncology, Vejle Hospital, University Hospital of Southern Denmark, DK-7100, Vejle, Denmark.
  • Santoni-Rugiu E; Department of Oncology, Næstved Hospital, DK-4700, Næstved, Denmark.
  • Ulhøi MP; Department of Pathology, Rigshospitalet, Copenhagen University Hospital, DK-2100, Copenhagen, Denmark.
  • Højgaard B; Department of Oncology, Aarhus University Hospital, DK-8000, Aarhus, Denmark.
  • Jensen MS; VIVE, Copenhagen, Denmark (The Danish Center for Social Science Research), DK-1052, Copenhagen, Denmark.
  • Dydensborg AB; Present address: Steno Diabetes Center, DK-2730, Herlev, Denmark.
  • Dünweber C; VIVE, Aarhus, Denmark (The Danish Center for Social Science Research), DK-8230, Åbyhøj, Denmark.
  • Hansen KH; Present address: Novo Nordisk, Søborg, DK-2860, Denmark.
Lung Cancer Manag ; 13(1): LMT68, 2024.
Article en En | MEDLINE | ID: mdl-38818369
ABSTRACT

Aim:

The main purpose of the present study was to investigate the labor market affiliation of ALK+ NSCLC patients in long-term treatment as well as overall survival and incidence/prevalence. Materials &

methods:

Nationwide retrospective study of all patients with ALK+ NSCLC in Denmark diagnosed between 2012 and 2018.

Results:

During the study period ALK+ NSCLC patients had a median overall survival of 44.0 months and a 7.8-fold increase in disease prevalence. Six months prior to diagnosis, 81% of ALK+ NSCLC patients ≤60 years of age were employed. At the end of the 18-month follow-up period, 36% were employed.

Conclusion:

ALK+ NSCLC patients have prolonged survival following diagnosis, but a large fraction of patients lose affiliation with the labor market.
The purpose of this study was to examine the employment status and survival of patients with ALK+ NSCLC who are undergoing long-term treatment. The researchers conducted a study analyzing data from all such patients diagnosed between 2012 and 2018 in Denmark. The results showed that ALK+ NSCLC patients had a median overall survival of 44.0 months and a that the number of patients increased almost eightfold during the study period. Prior to diagnosis, 81% of ALK+ NSCLC patients who were 60 years of age or younger were employed. However, at the end of the 18-month follow-up period, only 36% of these patients were still employed. In conclusion, ALK+ NSCLC patients tend to have prolonged survival after diagnosis. However, a considerable proportion of these patients lose their affiliation with the labor market, indicating the impact of the disease on employment status.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lung Cancer Manag Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Lung Cancer Manag Año: 2024 Tipo del documento: Article País de afiliación: Dinamarca Pais de publicación: Reino Unido