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Focused ultrasound as a treatment modality for gliomas.
Nwafor, Divine C; Obiri-Yeboah, Derrick; Fazad, Faraz; Blanks, William; Mut, Melike.
Afiliación
  • Nwafor DC; Department of Neurosurgery, University of Virginia, Charlottesville, VA, United States.
  • Obiri-Yeboah D; Department of Neurological Surgery, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, United States.
  • Fazad F; Department of Neurosurgery, University of Virginia, Charlottesville, VA, United States.
  • Blanks W; Department of Neurosurgery, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, United States.
  • Mut M; Department of Neurosurgery, University of Virginia, Charlottesville, VA, United States.
Front Neurol ; 15: 1387986, 2024.
Article en En | MEDLINE | ID: mdl-38813245
ABSTRACT
Ultrasound waves were initially used as a diagnostic tool that provided critical insights into several pathological conditions (e.g., gallstones, ascites, pneumothorax, etc.) at the bedside. Over the past decade, advancements in technology have led to the use of ultrasound waves in treating many neurological conditions, such as essential tremor and Parkinson's disease, with high specificity. The convergence of ultrasound waves at a specific region of interest/target while avoiding surrounding tissue has led to the coined term "focused ultrasound (FUS)." In tumor research, ultrasound technology was initially used as an intraoperative guidance tool for tumor resection. However, in recent years, there has been growing interest in utilizing FUS as a therapeutic tool in the management of brain tumors such as gliomas. This mini-review highlights the current knowledge surrounding using FUS as a treatment modality for gliomas. Furthermore, we discuss the utility of FUS in enhanced drug delivery to the central nervous system (CNS) and highlight promising clinical trials that utilize FUS as a treatment modality for gliomas.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Neurol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Front Neurol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza