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Topical lyophilized thrombin application improves wound healing for posterior spinal surgery.
Zhao, Yinjie; Liu, Ming; Li, Wenyao; Tao, Guocai.
Afiliación
  • Zhao Y; Department of Anesthesiology, Guiqian International General Hospital, Guiyang, 550024, China.
  • Liu M; Department of Orthopedics and Sports Medicine, Heyou International Hospital, Guangdong, 528000, China.
  • Li W; Department of Pain Management, Guigian International General Hospital, Gui Yang, 550024, China.
  • Tao G; Department of Anesthesiology, Guiqian International General Hospital, Guiyang, 550024, China.
Heliyon ; 10(10): e31335, 2024 May 30.
Article en En | MEDLINE | ID: mdl-38813190
ABSTRACT

Background:

The erector spinae plane block (ESPB) was proposed as a part of the postoperative multimodal analgesic regimen to improve pain management after posterior spinal surgery. However, ESPB might cause more surgical incisional wound exudate and poor wound healing, which might be improved after topical lyophilized thrombin application. Materials and

methods:

We performed a retrospective study on patients who received posterior spinal surgery between January 2018 and December 2021. These patients were assigned into three groups group A (general anesthesia), group B (general anesthesia with ESPB), and group C (general anesthesia with ESPB and topical 1000-unit thrombin application). Postoperative outcomes, including times of dressing changes, duration of suture removal, and incisional wound healing, were compared among these groups.

Results:

Our study included 89 patients, with 48, 20, and 21 patients in groups A, B, and C, respectively. Baseline demographics, height, weight, comorbidities, and operation duration were comparable among the three groups. Group B required statistically significantly more dressing changes and had a prolonged duration of suture removal than group A (9.4 ± 4.7 versus 6.5 ± 2.0 times, 16.2 ± 3.7 versus 14.2 ± 1.4 days, respectively), which could be statistically significantly improved after the thrombin application in group C. Group B also had more frequent poor wound healing (25.0 %), which could also be improved after the thrombin application (0.0 %).

Conclusions:

ESPB could cause more dressing changes and poor surgical wound healing after posterior spinal surgery, which could be improved by topical lyophilized thrombin powder application.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Heliyon Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Reino Unido