Clinical outcomes of nonvariceal upper gastrointestinal bleeding in nonagenarians and octogenarians: a comparative nationwide analysis.

Elfert, Khaled; Love, James; Elromisy, Esraa; Jaber, Fouad; Nayudu, Suresh; Ho, Sammy; Kahaleh, Michel

Elfert, Khaled; Love, James; Elromisy, Esraa; Jaber, Fouad; Nayudu, Suresh; Ho, Sammy; Kahaleh, Michel.

Afiliación

Elfert K; Department of Internal Medicine, SBH Health System, New York, NY.
Love J; Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.
Elromisy E; Tanta University Faculty of Medicine, Tanta, Egypt.
Jaber F; Department of Internal Medicine, University of Missouri-Kansas City School of Medicine, Kansas City, MO.
Nayudu S; Division of Gastroenterology, SBH Health System, New York, NY.
Ho S; Division of Gastroenterology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Kahaleh M; Division of Gastroenterology, Department of Medicine, Robert Wood Johnson University Hospital, New Brunswick, NJ, USA.

Clin Endosc ; 57(3): 342-349, 2024 May.

Article en En | MEDLINE | ID: mdl-38807362

ABSTRACT

ABSTRACT

BACKGROUND/

AIMS:

Nonagenarians will purportedly account for 10% of the United States population by 2050. However, no studies have assessed the outcomes of nonvariceal upper gastrointestinal bleeding (NVUGIB) in this age group.

METHODS:

The National Inpatient Sample database between 2016 and 2020 was used to compare the clinical outcomes of NVUGIB in nonagenarians and octogenarians and evaluate predictors of mortality and the use of esophagogastroduodenoscopy (EGD).

RESULTS:

Nonagenarians had higher in-hospital mortality than that of octogenarians (4% vs. 3%, p<0.001). EGD utilization (30% vs. 48%, p<0.001) and blood transfusion (27% vs. 40%, p<0.001) was significantly lower in nonagenarians. Multivariate logistic regression analysis revealed that nonagenarians with NVUGIB had higher odds of mortality (odds ratio [OR], 1.5; 95% confidence interval [CI], 1.3-1.7) and lower odds of EGD utilization (OR, 0.86; 95% CI, 0.83-0.89) than those of octogenarians.

CONCLUSIONS:

Nonagenarians admitted with NVUGIB have a higher mortality risk than that of octogenarians. EGD is used significantly in managing NVUGIB among nonagenarians; however, its utilization is comparatively lower than in octogenarians. More studies are needed to assess predictors of poor outcomes and the indications of EGD in this growing population.

Palabras clave

Esophagogastroduodenoscopy; Gastrointestinal hemorrhage; Nonagenarians; Octogenarians

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Clin Endosc Año: 2024 Tipo del documento: Article Pais de publicación: