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High-intensity interval training mitigates the progression of periodontitis and improves behavioural aspects in rats.
Pereira, Ramona Ramalho de Souza; Castro, Giselle Bicalho de; Magalhães, Caíque Olegário Diniz E; Costa, Karine Beatriz; Garcia, Bruna Caroline Chaves; Silva, Gabriela; Carvalho, Jaqueline do Carmo Lima; Machado, Alan Rodrigues Teixeira; Vieira, Etel Rocha; Cassilhas, Ricardo Cardoso; Pereira, Luciano José; Dias-Peixoto, Marco Fabrício; Andrade, Eric Francelino.
Afiliación
  • Pereira RRS; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Castro GB; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Magalhães CODE; Biological and Health Sciences Department, Federal University of the Jequitinhonha and Mucuri Valleys (UFVJM), Diamantina, Brazil.
  • Costa KB; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Garcia BCC; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Silva G; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Carvalho JDCL; Department of Exact Sciences, Universidade do Estado de Minas Gerais, João Monlevade, Minas Gerais, Brazil.
  • Machado ART; Department of Exact Sciences, Universidade do Estado de Minas Gerais, João Monlevade, Minas Gerais, Brazil.
  • Vieira ER; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Cassilhas RC; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Pereira LJ; Department of Health Sciences, Universidade Federal de Lavras (UFLA), Lavras, Minas Gerais, Brazil.
  • Dias-Peixoto MF; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
  • Andrade EF; Health Sciences Program, Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM), Diamantina, Brazil.
J Clin Periodontol ; 51(9): 1222-1235, 2024 09.
Article en En | MEDLINE | ID: mdl-38798054
ABSTRACT

AIM:

To investigate the effects of high-intensity interval training (HIIT) on periodontitis (PD) progression and behavioural outcomes. MATERIALS AND

METHODS:

Forty-eight Wistar rats were divided into four groups non-trained (NT); non-trained with PD; HIIT with PD; and HIIT. The HIIT protocol, involving daily treadmill sessions, spanned 8 weeks, with PD induced by ligature after the 6th week. Behavioural tests were conducted to assess anxiety and memory. Post euthanasia, we evaluated the systemic inflammatory profile and oxidative stress markers in the hippocampus and amygdala. A morphological evaluation and elemental composition analysis of the mandibular alveolar bone were performed.

RESULTS:

PD exacerbated alveolar bone level, bone surface damage and alterations in calcium and phosphorus percentages on the bone surface (p < .05), while HIIT attenuated these changes (p < .05). HIIT improved systemic inflammatory markers altered by PD (tumour necrosis factor [TNF]-α, interleukin [IL]-10, TNF-α/IL-10 and IL-1ß/IL-10 ratios, p < .05). PD animals exhibited lower total antioxidant capacity and levels of thiobarbituric acid reactive substances in the amygdala and hippocampus, respectively (p < .05). HIIT maintained these parameters at levels similar to those in NT animals. HIIT improved anxiety and memory outcomes altered by PD (p < .05).

CONCLUSIONS:

HIIT attenuates systemic inflammation, anxiety and memory outcomes promoted by PD.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Periodontitis / Condicionamiento Físico Animal / Conducta Animal / Ratas Wistar / Entrenamiento de Intervalos de Alta Intensidad Límite: Animals Idioma: En Revista: J Clin Periodontol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Periodontitis / Condicionamiento Físico Animal / Conducta Animal / Ratas Wistar / Entrenamiento de Intervalos de Alta Intensidad Límite: Animals Idioma: En Revista: J Clin Periodontol Año: 2024 Tipo del documento: Article País de afiliación: Brasil Pais de publicación: Estados Unidos