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Testing "Pits" Time Trade-Off: Can Data Quality be Improved by Removing Death From Valuation of Health States?
Liao, Meixia; Yang, Zhihao; Rand, Kim; Luo, Nan.
Afiliación
  • Liao M; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
  • Yang Z; Health Services Management Department, Guizhou Medical University, Guiyang, Guizhou Province, China.
  • Rand K; Health Services Research Center, Akershus University Hospital, Lørenskog, Norway; Maths in Health B.V., Rotterdam, The Netherlands.
  • Luo N; Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore. Electronic address: ephln@nus.edu.sg.
Value Health ; 27(9): 1261-1269, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38795961
ABSTRACT

OBJECTIVES:

Composite time trade-off (cTTO) often exhibits issues such as a value clustering at -1, potentially due to suboptimal valuation task design. We developed a novel time trade-off which uses the "pits" state as an anchor state and enables a unified time trade-off procedure for all health states (referred to as "pTTO"). This study aimed to test the pTTO for valuation of EQ-5D-5L health states.

METHODS:

A total of 120 members of the general public were invited to value 3 pairs of dominant/dominated EQ-5D-5L states using both cTTO and pTTO and the "pits" state using cTTO. We compared the pTTO with cTTO in terms of feasibility (interviewer-rated task-completing difficulty), acceptability (participant-reported task experience), value distribution, logical consistency, and discriminatory ability (using the standardized response mean, an effect size measure, derived from 3 pairwise comparisons of states with dominant/dominated relationship).

RESULTS:

The pTTO demonstrated similar feasibility to cTTO but slightly lower acceptability. The pTTO values exhibited a smoother and more continuous distribution compared with cTTO values. Relative to the cTTO, the pTTO showed higher individual-level logical consistency rate for the pairs comprising severe states (stringent criterion 53.04% vs 17.39%; less stringent criterion 82.61% vs 78.26%). The standardized response mean value based on pTTO values were higher than those based on cTTO values for the pair comprising severe states (0.388 vs -0.140).

CONCLUSIONS:

The pTTO appeared to be feasible and acceptable to value EQ-5D-5L states. The pTTO values were less clustered, more logically consistent, and discriminative compared with the cTTO values for severe health states.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Estado de Salud Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Value Health Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Estado de Salud Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Value Health Asunto de la revista: FARMACOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Singapur Pais de publicación: Estados Unidos