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Punctate Inner Choroidopathy (PIC) disease recurrence with inflammatory choroidal neovascular membrane (iCNVM) post-COVID-19 vaccine.
Scott, Daniel Andrew Richard; Niederer, Rachael Louise.
Afiliación
  • Scott DAR; Te Whatu Ora Health New Zealand Te Toka Tumai Auckland, Department of Ophthalmology, Greenlane Clinical Centre, Auckland, New Zealand.
  • Niederer RL; University of Auckland, Faculty of Medical and Health Sciences, Department of Ophthalmology, Auckland, New Zealand.
Eur J Ophthalmol ; 34(5): NP78-NP82, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38794849
ABSTRACT

PURPOSE:

To report a recurrence of punctate inner choroidopathy (PIC) with an inflammatory choroidal neovascular membrane (iCNVM) after the Pfizer-BioNTech COVID-19 vaccine.

METHODS:

Case report.

RESULTS:

A 38-year-old female with a history of myopia and previous episodes of PIC and iCNVM presented with distorted vision in her right eye, seven days after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine. The patient exhibited active PIC lesions with iCNVM confirmed on multimodal imaging. Treatment with a combination of oral corticosteroids and intravitreal anti-VEGF injection led to disease resolution. Subsequent COVID-19 vaccinations, administered while the patient was immunosuppressed, did not lead to disease relapse. However, relapse occurred following the fourth COVID-19 vaccine, when the patient was not immune suppressed.

CONCLUSION:

This case highlights the potential risk of PIC disease relapse following COVID-19 vaccination. Further research is needed to investigate the relationship between COVID-19 vaccination and PIC exacerbation, as well as to determine optimal management strategies in this population, including close observation and consideration of prophylactic immune suppression at the time of COVID-19 vaccine for high-risk individuals.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recurrencia / Angiografía con Fluoresceína / Neovascularización Coroidal / Tomografía de Coherencia Óptica / Vacunas contra la COVID-19 / SARS-CoV-2 / COVID-19 Límite: Adult / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Recurrencia / Angiografía con Fluoresceína / Neovascularización Coroidal / Tomografía de Coherencia Óptica / Vacunas contra la COVID-19 / SARS-CoV-2 / COVID-19 Límite: Adult / Female / Humans Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Nueva Zelanda Pais de publicación: Estados Unidos