Your browser doesn't support javascript.
loading
Effect of Intermittent vs. Continuous Energy Restriction on Visceral Fat: Protocol for The Healthy Diet and Lifestyle Study 2 (HDLS2).
Lewis, Michelle Y; Yonemori, Kim; Ross, Alison; Wilkens, Lynne R; Shepherd, John; Cassel, Kevin; Stenger, Andrew; Rettenmeier, Christoph; Lim, Unhee; Boushey, Carol; Le Marchand, Loïc.
Afiliación
  • Lewis MY; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Yonemori K; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Ross A; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Wilkens LR; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Shepherd J; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Cassel K; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Stenger A; MRI Research Center, John A. Burns School of Medicine, University of Hawai'i, Honolulu, Hi 96813, USA.
  • Rettenmeier C; MRI Research Center, John A. Burns School of Medicine, University of Hawai'i, Honolulu, Hi 96813, USA.
  • Lim U; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Boushey C; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
  • Le Marchand L; Population Sciences in the Pacific Program, University of Hawai'i Cancer Center, Honolulu, HI 96813, USA.
Nutrients ; 16(10)2024 May 14.
Article en En | MEDLINE | ID: mdl-38794715
ABSTRACT
Obesity in the United States and Western countries represents a major health challenge associated with an increased risk of metabolic diseases, including cardiovascular disease, hypertension, diabetes, and certain cancers. Our past work revealed a more pronounced obesity-cancer link in certain ethnic groups, motivating us to develop a tailored dietary intervention called the Healthy Diet and Lifestyle 2 (HDLS2). The study protocol is described herein for this randomized six-month trial examining the effects of intermittent energy restriction (52 Diet) plus the Mediterranean dietary pattern (IER + MED) on visceral adipose tissue (VAT), liver fat, and metabolic biomarkers, compared to a standard MED with daily energy restriction (DER + MED), in a diverse participant group. Using MRI and DXA scans for body composition analysis, as well as metabolic profiling, this research aims to contribute to nutritional guidelines and strategies for visceral obesity reduction. The potential benefits of IER + MED, particularly regarding VAT reduction and metabolic health improvement, could be pivotal in mitigating the obesity epidemic and its metabolic sequelae. The ongoing study will provide essential insights into the efficacy of these energy restriction approaches across varied racial/ethnic backgrounds, addressing an urgent need in nutrition and metabolic health research. Registered Trial, National Institutes of Health, ClinicalTrials.gov (NCT05132686).
Asunto(s)
Palabras clave
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Restricción Calórica / Dieta Mediterránea / Grasa Intraabdominal Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Nutrients Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Restricción Calórica / Dieta Mediterránea / Grasa Intraabdominal Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Nutrients Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Suiza