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Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents.
Sisáková, Martina; Helánová, Katerina; Hnatkova, Katerina; Andrsová, Irena; Novotný, Tomás; Malik, Marek.
Afiliación
  • Sisáková M; Department of Internal Medicine and Cardiology, University Hospital Brno, Jihlavská 20, 625 00 Brno, Czech Republic.
  • Helánová K; Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, 62 500 Brno, Czech Republic.
  • Hnatkova K; Department of Internal Medicine and Cardiology, University Hospital Brno, Jihlavská 20, 625 00 Brno, Czech Republic.
  • Andrsová I; Department of Internal Medicine and Cardiology, Faculty of Medicine, Masaryk University, 62 500 Brno, Czech Republic.
  • Novotný T; National Heart and Lung Institute, Imperial College, London SW3 6LY, UK.
  • Malik M; Department of Internal Medicine and Cardiology, University Hospital Brno, Jihlavská 20, 625 00 Brno, Czech Republic.
J Clin Med ; 13(10)2024 May 14.
Article en En | MEDLINE | ID: mdl-38792438
ABSTRACT
Background/

Objective:

The relationship between heart rate and heart rate variability (HRV) indices has been repeatedly studied in adults but limited data are available on the relationship in paediatric populations.

Methods:

Continuous 12-lead electrocardiograms were recorded in 1016 healthy children and adolescents (534 females) aged 4 to 19 years during postural manoeuvres with rapid changes between 10-min positions of supine → sitting → standing → supine → standing → sitting → supine. In each position, the averaged RR interval was measured together with four HRV indices, namely the SDNN, RMSSD, quasi-normalised high-frequency components (qnHF), and the proportions of low- and high-frequency components (LF/HF). In each subject, the slope of the linear regression between the repeated HRV measurements and the corresponding RR interval averages was calculated.

Results:

The intra-subject regression slopes, including their confidence intervals, were related to the age and sex of the subjects. The SDNN/RR, RMSSD/RR, and qnHF/RR slopes were significantly steeper (p < 0.001) and the (LF/HF)/RR slopes were significantly shallower (p < 0.001) in younger children compared to older children and adolescents.

Conclusions:

The study suggests that sympathetic and vagal influences on heart rate are present in both younger and older children. With advancing age, the sympatho-vagal balance gradually develops and allows the vagal control to suppress the sympathetic drive towards higher heart rates seen in younger age children.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Suiza

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: República Checa Pais de publicación: Suiza