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Association between Obesity and Atrial Function in Patients with Non-Valvular Atrial Fibrillation: An Echocardiographic Study.
Pucci, Martina; Gammaldi, Vittoria; Capece, Luca Maria; Paoletta, Daniele; Iervolino, Adelaide; Pontoriero, Mariateresa; Iacono, Marina; Megaro, Pasquale; Esposito, Roberta.
Afiliación
  • Pucci M; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Gammaldi V; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Capece LM; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Paoletta D; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Iervolino A; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Pontoriero M; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Iacono M; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Megaro P; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
  • Esposito R; Department of Clinical Medicine and Surgery, Federico II University Hospital, 80131 Naples, Italy.
J Clin Med ; 13(10)2024 May 14.
Article en En | MEDLINE | ID: mdl-38792436
ABSTRACT

Background:

Obesity is a public health problem which prevalence has increased worldwide and is associated with different degrees of hemodynamic alterations and structural cardiac changes. The aim of the study is to investigate the impact of body mass index (BMI) on left atrial function using standard and advanced echocardiography in a population of patients with non-valvular atrial fibrillation (AF).

Methods:

395 adult patients suffering from non-valvular AF, divided into three tertiles based on BMI value, carry out a cardiological examination with standard and advanced echocardiography.

Results:

Peak atrial longitudinal strain (PALS), a measure of left atrial function, is lower in the tertile with highest BMI (14.3 ± 8.2%) compared to both the first (19 ± 11.5%) and the second tertile (17.7 ± 10.6%) in a statistically significant manner (p < 0.002). Furthermore, BMI is significantly associated independent with the PALS by multilinear regression analysis, even after correction of the data for CHA2DS2-VASc score, left ventricular mass index, left ventricular ejection fraction, E/E' ratio and systolic pulmonary arterial pressure (coefficient standardized ß = -0.127, p < 0.02; Cumulative R2 = 0.41, SEE = 0.8%, p < 0.0001).

Conclusions:

BMI could be considered an additional factor in assessing cardiovascular risk in patients with non-valvular atrial fibrillation, in addition to the well-known CHA2DS2-VASc score.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Clin Med Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Suiza