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The Role of Traditional Chinese Medicine in the Management of Cervical Cancer.
Wu, Dailin; Zhou, Ruisheng; Chen, Hongyu; Pan, Yanli; Tang, Ying; Zhou, Daihan.
Afiliación
  • Wu D; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China.
  • Zhou R; The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China.
  • Chen H; Internal Medicine-Oncology, Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine, Shenzhen 518034, P. R. China.
  • Pan Y; Gushengtang Medicine-Oncology, Guangzhou 518112, P. R. China.
  • Tang Y; Institute of Tumor, Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China.
  • Zhou D; Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, P. R. China.
Am J Chin Med ; 52(4): 1013-1025, 2024.
Article en En | MEDLINE | ID: mdl-38790084
ABSTRACT
Globally, cervical cancer poses a substantial public health challenge, with low and middle-income countries bearing the highest burden [Rajkhowa, P., D.S. Patil, S.M. Dsouza, P. Narayanan and H. Brand. Evidence on factors influencing HPV vaccine implementation in South Asia a scoping review. Glob. Public Health 18 2288269, 2023]. The incidence rate ranks second highest among female malignant tumors in China, following only breast cancer. The prognosis of advanced cervical cancer is extremely poor, with a 5-year progression-free survival (PFS) rate of only 15%, and the treatment of advanced recurrent or metastatic cervical cancer remains a huge challenge. An increasing amount of evidence suggests that traditional Chinese medicine (TCM) can significantly enhance sensitivity to chemotherapeutic drugs, strengthen antitumor effects, and notably improve adverse reactions associated with cancer such as fatigue and bone marrow suppression. In recent years, the therapeutic effects and mechanisms of Chinese herbal medicines, such as the Guizhi-Fuling-decoction, the compound Yangshe granule, Huangqi, and Ginseng, herbal monomers (e.g., Ginsenoside Rh2, Tanshinone IIA, and Tetrandrine), and the related extracts and compound formulations, have received extensive attention for the treatment of cervical cancer. This paper reviews the research progress of TCM in cervical cancer. In addition, we reported a case of an advanced cervical cancer patient with multiple abdominal and pelvic metastasis who initially received chemotherapy, was then treated with TCM alone, and subsequently survived for 22 years. The model of whole-process management with TCM can enable more cancer patients to obtain longer survival periods.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Neoplasias del Cuello Uterino / Medicina Tradicional China Límite: Female / Humans Idioma: En Revista: Am J Chin Med Año: 2024 Tipo del documento: Article Pais de publicación: Singapur
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Medicamentos Herbarios Chinos / Neoplasias del Cuello Uterino / Medicina Tradicional China Límite: Female / Humans Idioma: En Revista: Am J Chin Med Año: 2024 Tipo del documento: Article Pais de publicación: Singapur