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Utilizing fMRI to Guide TMS Targets: the Reliability and Sensitivity of fMRI Metrics at 3 T and 1.5 T.
Ge, Qiu; Lock, Matthew; Yang, Xue; Ding, Yuejiao; Yue, Juan; Zhao, Na; Hu, Yun-Song; Zhang, Yong; Yao, Minliang; Zang, Yu-Feng.
Afiliación
  • Ge Q; Center for Cognition and Brain Disorders, the Affiliated Hospital of Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Lock M; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Zhejiang, Hangzhou, China.
  • Yang X; Institute of Psychological Sciences, Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Ding Y; Center for Cognition and Brain Disorders, the Affiliated Hospital of Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Yue J; Center for Cognition and Brain Disorders, the Affiliated Hospital of Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Zhao N; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Zhejiang, Hangzhou, China.
  • Hu YS; Institute of Psychological Sciences, Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Zhang Y; Center for Cognition and Brain Disorders, the Affiliated Hospital of Hangzhou Normal University, Zhejiang, Hangzhou, China.
  • Yao M; Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Zhejiang, Hangzhou, China.
  • Zang YF; Institute of Psychological Sciences, Hangzhou Normal University, Zhejiang, Hangzhou, China.
Neuroinformatics ; 2024 May 23.
Article en En | MEDLINE | ID: mdl-38780699
ABSTRACT
US Food and Drug Administration (FDA) cleared a Transcranial Magnetic Stimulation (TMS) system with functional Magnetic Resonance Imaging-guided (fMRI) individualized treatment protocol for major depressive disorder, which employs resting state-fMRI (RS-fMRI) functional connectivity (FC) to pinpoint the target individually to increase the accuracy and effeteness of the stimulation. Furthermore, task activation-guided TMS, as well as the use of RS-fMRI local metrics for targeted the specific abnormal brain regions, are considered a precise scheme for TMS targeting. Since 1.5 T MRI is more available in hospitals, systematic evaluation of the test-retest reliability and sensitivity of fMRI metrics on 1.5 T and 3 T MRI may provide reference for the application of fMRI-guided individualized-precise TMS stimulation. Twenty participants underwent three RS-fMRI scans and one scan of finger-tapping task fMRI with self-initiated (SI) and visual-guided (VG) conditions at both 3 T and 1.5 T. Then the location reliability derived by FC (with three seed regions) and peak activation were assessed by intra-individual distance. The test-retest reliability and sensitivity of five RS-fMRI local metrics were evaluated using intra-class correlation and effect size, separately. The intra-individual distance of peak activation location between 1.5 T and 3 T was 15.8 mm and 19 mm for two conditions, respectively. The intra-individual distance for the FC derived targets at 1.5 T was 9.6-31.2 mm, compared to that of 3 T (7.6-31.1 mm). The test-retest reliability and sensitivity of RS-fMRI local metrics showed similar trends on 1.5 T and 3 T. These findings hasten the application of fMRI-guided individualized TMS treatment in clinical practice.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neuroinformatics Asunto de la revista: INFORMATICA MEDICA / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Neuroinformatics Asunto de la revista: INFORMATICA MEDICA / NEUROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: China Pais de publicación: Estados Unidos