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Spinal cord involvement in progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome.
Moussaoui, Nisrine El; Lambert, Nicolas; Moussaoui, Majdouline El; Bianchi, Elettra; Léonard, Philippe; Moïse, Martin; Maquet, Pierre.
Afiliación
  • Moussaoui NE; Faculty of Medicine, University of Liège, Liège, Belgium.
  • Lambert N; Department of Neurology, University Hospital of Liège, Liège, Belgium. nicolas.lambert@chuliege.be.
  • Moussaoui ME; Service de Neurologie, CHU de Liège, Avenue de l'Hopital, 1, 4000, Liège, Belgium. nicolas.lambert@chuliege.be.
  • Bianchi E; Department of Infectious Diseases and General Internal Medicine, University Hospital of Liège, Liège, Belgium.
  • Léonard P; Department of Anatomopathology, University Hospital of Liège, Liège, Belgium.
  • Moïse M; Department of Infectious Diseases and General Internal Medicine, University Hospital of Liège, Liège, Belgium.
  • Maquet P; Department of Radiology, University Hospital of Liège, Liège, Belgium.
J Neurovirol ; 30(2): 208-213, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38778006
ABSTRACT
Progressive multifocal leukoencephalopathy (PML) is an opportunistic infectious demyelinating disease of the central nervous system caused by JC polyomavirus predominantly affecting immunocompromised individuals. Nowadays, HIV, hematological malignancies and iatrogenic immune suppression account for most PML cases. For unknown reasons, spinal cord is classically protected from PML lesions. Here, we report the course of a patient harboring spinal cord lesions in the context of PML with immune reconstitution inflammatory syndrome and review the eight other cases reported in the literature so far. Then, we discuss the evolving spectrum of PML over recent years, potentially making its diagnosis more challenging.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Médula Espinal / Leucoencefalopatía Multifocal Progresiva / Virus JC / Síndrome Inflamatorio de Reconstitución Inmune Límite: Humans Idioma: En Revista: J Neurovirol Asunto de la revista: NEUROLOGIA / VIROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Médula Espinal / Leucoencefalopatía Multifocal Progresiva / Virus JC / Síndrome Inflamatorio de Reconstitución Inmune Límite: Humans Idioma: En Revista: J Neurovirol Asunto de la revista: NEUROLOGIA / VIROLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Estados Unidos