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Ultrasonographic Detective Flow Imaging for Evaluating Parathyroid Adenoma in Patients with Primary Hyperparathyroidism.
Akasu, Haruki; Jikuzono, Tomoo; Matsui, Mami; Sen, Masaomi; Saitou, Marie; Ishibashi, Osamu; Sugitani, Iwao.
Afiliación
  • Akasu H; Department of Endocrine Surgery, Nippon Medical School Musashi Kosugi Hospital.
  • Jikuzono T; Department of Endocrine Surgery, Nippon Medical School.
  • Matsui M; Department of Endocrine Surgery, Nippon Medical School.
  • Sen M; Department of Endocrine Surgery, Nippon Medical School.
  • Saitou M; Department of Endocrine Surgery, Nippon Medical School.
  • Ishibashi O; Department of Endocrine Surgery, Nippon Medical School.
  • Sugitani I; Laboratory of Biological Macromolecules, Department of Applied Life Sciences, Graduate School of Life & Environmental Sciences, Osaka Prefecture University.
J Nippon Med Sch ; 91(2): 227-232, 2024.
Article en En | MEDLINE | ID: mdl-38777783
ABSTRACT

BACKGROUND:

Detective flow imaging (DFI) is a new imaging technology that displays low-velocity blood flow, which is difficult to visualize on conventional color Doppler ultrasonography (CDU). In this study, we compared the usefulness of DFI with that of CDU and methoxy-isobutyl-isonitrile (MIBI) scintigraphy for detecting parathyroid adenoma (PA) in patients with primary hyperparathyroidism (PHPT).

METHODS:

From March 2021 to March 2023, 87 PHPT patients underwent surgery, and 66 had a single PA. We performed preoperative conventional ultrasonography with CDU, MIBI scintigraphy, and DFI for 42 patients (5 males and 37 females; mean age 61.6 ± 15.4 years).

RESULTS:

MIBI scintigraphy detected PA in 85.7% (36/42) patients, and both CDU and DFI detected PA in all patients. The rates of vascularity in PA detected by CDU and DFI were 71.4% (30/42) and 85.7% (36/42), respectively. Vascularity was detected by DFI in 6 patients who were negative for vascularity on MIBI scintigraphy. Furthermore, DFI detected blood supply in 6 of the 12 patients with undetectable blood supply on CDU. Fisher's exact test revealed that high or low blood flow, as determined by DFI, was significantly associated with detection of feeding vessels in PA by CDU (P < 0.001).

CONCLUSIONS:

DFI was useful for preoperative detection of PA blood flow.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Paratiroides / Adenoma / Ultrasonografía Doppler en Color / Hiperparatiroidismo Primario Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Nippon Med Sch Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Japón

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias de las Paratiroides / Adenoma / Ultrasonografía Doppler en Color / Hiperparatiroidismo Primario Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: J Nippon Med Sch Asunto de la revista: MEDICINA Año: 2024 Tipo del documento: Article Pais de publicación: Japón