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Clinical Practice Guideline-Inconsistent Management of Fertility Preservation in Pediatric Cancer Patients in Community Settings: A Children's Oncology Group Study.
Grimes, Allison C; Sugalski, Aaron J; Nuño, Michelle M; Ramakrishnan, Subhash; Beauchemin, Melissa P; Robinson, Paula D; Santesso, Nancy; Walsh, Alexandra M; Wrightson, Andrea R; Yu, Lolie C; Parsons, Susan K; Sung, Lillian; Dupuis, L Lee.
Afiliación
  • Grimes AC; University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.
  • Sugalski AJ; University of Texas Health Science Center San Antonio, San Antonio, Texas, USA.
  • Nuño MM; Children's Oncology Group, Monrovia, California, USA.
  • Ramakrishnan S; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, California, USA.
  • Beauchemin MP; Children's Oncology Group, Monrovia, California, USA.
  • Robinson PD; Columbia University Irving Medical Center, New York, New York, USA.
  • Santesso N; Pediatric Oncology Group of Ontario, Toronto, Canada.
  • Walsh AM; Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Canada.
  • Wrightson AR; Center for Cancer and Blood Disorders, Phoenix Children's Hospital, University of Arizona, Phoenix, Arizona, USA.
  • Yu LC; Clinical Research Nurse Coordinator, Nemours Center for Cancer and Blood Disorders, Wilmington, Delaware, USA.
  • Parsons SK; LSUHSC/Children's Hospital, New Orleans, Louisiana, USA.
  • Sung L; Institute for Clinical Research and Health Policy Studies and Division of Hematology/Oncology, Tufts Medical Center, Boston, Massachusetts, USA.
  • Dupuis LL; Research Institute, The Hospital for Sick Children, Toronto, Canada.
J Adolesc Young Adult Oncol ; 2024 May 21.
Article en En | MEDLINE | ID: mdl-38770790
ABSTRACT

Background:

The primary objective was to measure adherence to clinical practice guideline (CPG) recommendations for fertility preservation (FP) in pediatric cancer patients treated in National Cancer Institute Community Oncology Research Program (NCORP) sites. Secondary objectives were to describe factors such as site size associated with CPG-inconsistent care delivery and cryopreservation completion.

Methods:

This retrospective, multicenter study included patients 15 to 21 years old with a first cancer diagnosis from January 2014 through December 2015 who were previously enrolled to a Children's Oncology Group (COG) study and received care at a participating NCORP site. Patients were randomly selected from a list generated by the COG for chart review by participating sites. Primary outcome was care delivery that was inconsistent with a strong CPG recommendation on FP, namely discussion and offering of FP options before cancer treatment initiation, as adjudicated centrally by a panel.

Results:

A total of 129 patients from 25 sites were included. Among these, 48% (62/129) received CPG-inconsistent care. Most CPG-inconsistent care was due to lack of FP discussion documentation (93.5%, 58/62). Small site size, treatment at a pediatric (vs mixed adult/pediatric) site, and female sex were associated with higher odds of CPG-inconsistent care delivery.

Conclusions:

Newly diagnosed pediatric cancer patients often received CPG-inconsistent care for FP, with disproportionate gaps noted for females, and those treated at smaller or pediatric NCORP sites. The primary reason for CPG-inconsistent care is lack of FP discussion from clinicians. Opportunities to improve FP CPG implementation are highlighted.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Adolesc Young Adult Oncol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Adolesc Young Adult Oncol Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos