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Emerging Medications and Strategies in Acute Pain Management: Evolving Role of Novel Sodium and Calcium Channel Blockers, Peptide-Based Pharmacologic Drugs, and Non-Medicinal Methods.
Kaye, Alan D; Greene, Driskell R; Nguyen, Catherine; Ragland, Amanda; Granger, Mason P; Wilhite, William Peyton; Dufrene, Kylie; Shekoohi, Sahar; Robinson, Christopher L.
Afiliación
  • Kaye AD; Department of Anesthesiology, Department of Pharmacology, Toxicology, and Neurosciences, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Greene DR; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Nguyen C; School of Medicine, Louisiana State University Health Sciences Center, 2020 Gravier Street, New Orleans, 70112, LA, USA.
  • Ragland A; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Granger MP; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Wilhite WP; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Dufrene K; School of Medicine, Louisiana State University Health Sciences Center, Shreveport, LA, 71103, USA.
  • Shekoohi S; Department of Anesthesiology, Louisiana State University Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71103, USA. sahar.shekoohi@lsuhs.edu.
  • Robinson CL; Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA, 02215, USA.
Curr Pain Headache Rep ; 28(9): 853-862, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38761297
ABSTRACT
PURPOSE OF REVIEW The present investigation evaluated integration of novel medication technology to enhance treatment options, while improving patient outcomes in acute pain management. In this regard, we focused on determining the role of development and utilization of cutting-edge pharmaceutical advancements, such as targeted drug delivery systems, as well as non-pharmacologic interventions in addressing acute pain states. Further research in this area is warranted related to the need for increased patient comfort and reduced adverse effects. RECENT

FINDINGS:

Recent innovations and techniques are discussed including pharmacologic drugs targeting sodium and calcium channels, peptide-based pharmacologic drugs, and non-medicinal methods of alleviating pain such as soothing music or virtual reality. The present investigation included review of current literature on the application of these innovative technologies, analyzing mechanisms of action, pharmacokinetics, and clinical effectiveness. Our study also investigated the potential benefits in terms of pain relief, reduced side effects, and improved patient adherence. The research critically examines the challenges and considerations associated with implementing these technologies in acute pain management, considering factors like cost, accessibility, and regulatory aspects. Additionally, case studies and clinical trials are highlighted which demonstrate practical implications of these novel medication technologies in real-world scenarios. The findings aim to provide healthcare professionals with a comprehensive understanding of the evolving landscape in acute pain management while guiding future research and clinical practices toward optimizing their use in enhancing patient care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bloqueadores de los Canales de Calcio / Dolor Agudo / Manejo del Dolor Límite: Humans Idioma: En Revista: Curr Pain Headache Rep Asunto de la revista: FISIOLOGIA / NEUROLOGIA / PSICOFISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bloqueadores de los Canales de Calcio / Dolor Agudo / Manejo del Dolor Límite: Humans Idioma: En Revista: Curr Pain Headache Rep Asunto de la revista: FISIOLOGIA / NEUROLOGIA / PSICOFISIOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos