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Social relationships and their impact on health-related quality of life in a long-term breast cancer survivor cohort.
Belau, Matthias Hans; Jung, Lisa; Maurer, Tabea; Obi, Nadia; Behrens, Sabine; Seibold, Petra; Becher, Heiko; Chang-Claude, Jenny.
Afiliación
  • Belau MH; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Jung L; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Maurer T; Cancer Epidemiology, University Medical Center Hamburg-Eppendorf, University Cancer Center Hamburg, Hamburg, Germany.
  • Obi N; Department of Medical Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Behrens S; Institute of Medical Biometry and Epidemiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Seibold P; Institute for Occupational and Maritime Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Becher H; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
  • Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany.
Cancer ; 130(18): 3210-3218, 2024 Sep 15.
Article en En | MEDLINE | ID: mdl-38758821
ABSTRACT

BACKGROUND:

Health-related quality of life (HRQOL) has become increasingly important for breast cancer survivors, but clinically relevant declines often persist for many years after treatment. This study aimed to investigate whether social relationships can mitigate or prevent this decline in HRQOL.

METHODS:

Data were used from the German population-based Mamma Carcinoma Risk Factor Investigation (MARIE) cohort of 2022 breast cancer cases with follow-up information for more than 15 years after diagnosis. Correlations between social integration, social support, and global health status (GHS) as an overall measure of HRQOL were analyzed, and linear regression analysis was performed with structural equation modeling.

RESULTS:

The majority of participants reported high levels of social integration and social support and moderate levels of GHS. Social integration 5 years after diagnosis was associated with GHS 5 years after diagnosis (ß = 1.12; 95% CI, 0.25-1.99), but no longitudinal effects were found. Social support 5 years after diagnosis was associated with better GHS 5 years (ß = 0.42; 95% CI, 0.36-0.48) and 10 years after diagnosis (ß = 0.12; 95% CI, 0.02-0.22), whereas social support 10 years after diagnosis was associated with GHS 10 years (ß = 0.29; 95% CI, 0.20-0.39) and 15 years after diagnosis (ß = 0.10; 95% CI, 0.01-0.21).

CONCLUSIONS:

These results confirm that social relationships positively influence HRQOL in long-term breast cancer survivors and that their association should receive more attention clinically and beyond routine care.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Apoyo Social / Neoplasias de la Mama / Supervivientes de Cáncer Límite: Adult / Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Cancer Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Calidad de Vida / Apoyo Social / Neoplasias de la Mama / Supervivientes de Cáncer Límite: Adult / Aged / Female / Humans / Middle aged País/Región como asunto: Europa Idioma: En Revista: Cancer Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: Estados Unidos