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Commissioning and Validation of CT Number to SPR Calibration in Carbon Ion Therapy Facility.
Miyasaka, Yuya; Kanai, Takayuki; Souda, Hikaru; Yamazawa, Yoshifumi; Lee, Sung Hyun; Chai, Hongbo; Sato, Hiraku; Iwai, Takeo.
Afiliación
  • Miyasaka Y; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
  • Kanai T; Department of Radiation Oncology, Tokyo Women's Medical University, Shinjuku, Tokyo, Japan.
  • Souda H; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
  • Yamazawa Y; Department of Radiology, Yamagata University Hospital, Yamagata, Japan.
  • Lee SH; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
  • Chai H; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
  • Sato H; Department of Radiology, Yamagata University Faculty of Medicine, Yamagata, Japan.
  • Iwai T; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
Int J Part Ther ; 11: 100011, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38757079
ABSTRACT

Purpose:

We performed computed tomography (CT)-stopping power ratio (SPR) calibration in a carbon-ion therapy facility and evaluated SPR estimation accuracy. Materials and

Methods:

A polybinary tissue model method was used for the calibration of CT numbers and SPR. As a verification by dose calculation, we created a virtual phantom to which the CT-SPR calibration table was applied. Then, SPR was calculated from the change in the range of the treatment planning beam when changing to 19 different CT numbers, and the accuracy of the treatment planning system (TPS) calculation of SPR values from the CT-SPR calibration table was validated. As a verification by measurement, 5 materials (water, milk, olive oil, ethanol, 40% K2HPO4) were placed in a container, and the SPR was obtained by measurement from the change in the range of the beam that passed through the materials.

Results:

The results of the dose calculations of the TPS showed that the results agreed within 1% for the lower CT numbers up to 1000 HU, but there was a difference of 3.0% in the higher CT number volume. The difference between the SPR calculated by TPS and the SPR caused by the difference in the energy of the incident particles agreed within 0.51%. The accuracy of SPR estimation was measured, and the error was within 2% for all materials tested.

Conclusion:

These results indicate that the SPR estimation errors are within the range of errors that can be expected in particle therapy. From commissioning and verification results, the CT-SPR calibration table obtained during this commissioning process is clinically applicable.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Part Ther Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Int J Part Ther Año: 2024 Tipo del documento: Article País de afiliación: Japón Pais de publicación: Estados Unidos