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Pembrolizumab-Induced Pancreatitis: Take It With a Grain of Salt.
Gajjar, Prachi C; Parmar, Parth; Gajjar, Hetvi; Upreti, Shikha; Shah, Munir.
Afiliación
  • Gajjar PC; Internal Medicine, Western Reserve Health Education, Warren, USA.
  • Parmar P; Internal Medicine, Western Reserve Health Education, Warren, USA.
  • Gajjar H; Internal Medicine, Pramukhswami Medical College - Karamsad, Karamsad, IND.
  • Upreti S; Internal Medicine, Ross University School of Medicine, Miami, USA.
  • Shah M; Infectious Disease, Western Reserve Health Education, Warren, USA.
Cureus ; 16(4): e58417, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38756289
ABSTRACT
Keytruda (pembrolizumab) is an immunomodulator that prevents the interaction between programmed cell death protein (PD-1) and programmed death ligand (PD-L1/2) on immune cells and tumour cells, thereby preventing T cell dysfunction. At times, mounting a strong immune response against tumour cells may not spare normal cells, leading to a variety of multisystemic adverse effects. With this, we present a case of a 64-year-old male who developed acute pancreatitis after completing eight cycles of Keytruda for castrate-resistant metastatic prostate cancer for six months, after all other causes of pancreatitis were excluded.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Cureus Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Estados Unidos