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Long-term functional success and patient-reported outcomes after female one-stage buccal mucosal graft urethroplasty.
Klemm, J; Marks, P; Schulz, R J; Filipas, D K; Stelzl, D R; Dahlem, R; Fisch, M; Vetterlein, M W.
Afiliación
  • Klemm J; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Marks P; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Schulz RJ; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Filipas DK; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Stelzl DR; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Dahlem R; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Fisch M; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Vetterlein MW; Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: m.vetterlein@uke.de.
Actas Urol Esp (Engl Ed) ; 2024 May 14.
Article en En, Es | MEDLINE | ID: mdl-38754730
ABSTRACT
INTRODUCTION AND

OBJECTIVES:

Female urethral strictures are a rare condition that significantly impacts patients' quality of life. Patient-reported outcomes are crucial, yet data regarding sexual function and treatment satisfaction are scarce. We aimed to provide insights from a reconstructive referral center. PATIENTS AND

METHODS:

We conducted a retrospective analysis of women treated with ventral onlay one-stage buccal mucosa graft urethroplasty for urethral strictures between 2009-2023. We assessed objective (retreatment-free survival, ΔQmax) and subjective outcomes (validated patient-reported outcomes).

RESULTS:

Of 12 women, 83% and 17% had iatrogenic and idiopathic strictures, respectively. Median number of prior interventions was 6. Strictures were located meatal and mid-urethral in 25% and 75%, respectively, 22% had the bladder neck involved. Median graft length was 2 cm. At median follow-up of 66 months, 33% of patients underwent stricture retreatment, but only one case occurred within the first 2 years postoperatively. The median improvement in maximum flow rate (ΔQmax) was 10 ml/s. Median International Consultation on Incontinence Questionnaire Female Lower Urinary Tract Symptoms Modules (ICIQ-FLUTS) scores were 8 for filling symptoms, 6 for voiding symptoms, and 3 for incontinence symptoms. Median ICIQ-FLUTSsex score was 4. Higher scores indicate a higher symptom burden. Median ICIQ-Satisfaction outcome and satisfaction scores were 18 and 7, respectively, reflecting high treatment satisfaction.

CONCLUSIONS:

Buccal mucosal graft urethroplasty by ventral onlay for female urethral strictures yields effective, durable, and positively received outcomes. However, larger studies across multiple institutions are necessary to further assess its efficacy, especially regarding patient-reported experiences and sexual function.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En / Es Revista: Actas Urol Esp (Engl Ed) Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: España
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En / Es Revista: Actas Urol Esp (Engl Ed) Año: 2024 Tipo del documento: Article País de afiliación: Alemania Pais de publicación: España