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Prognostic value of geriatric and cardiac parameters for one-year mortality in older heart failure patients. A multicentre, observational, prospective study.
Kestens, L; Billet, S; Hens, L; Velghe, A; Piers, R.
Afiliación
  • Kestens L; Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.
  • Billet S; Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.
  • Hens L; Department of Cardiology, Ghent University Hospital, Ghent, and Department of Cardiology AZ Groeninge, Kortrijk, Belgium.
  • Velghe A; Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.
  • Piers R; Department of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium.
Acta Clin Belg ; 79(2): 113-120, 2024 Apr.
Article en En | MEDLINE | ID: mdl-38752847
ABSTRACT

PURPOSE:

Heart failure is prevalent among older people and has a poor prognosis. The aim of this study is to identify potential prognostic, geriatric, and cardiac parameters which could help clinicians identify older heart failure patients at high risk for one-year mortality.

METHODS:

The multicentre, observational cohort study which included 147 heart failure patients aged ≥75 years, hospitalized in the cardiac or geriatric department in two hospitals. One-year survival was the outcome measure. For univariate analysis Chi-square test and independent sample T-test were used; for multivariate analysis Logistic regression and Cox regression for time-dependent analysis.

RESULTS:

One-year mortality was 28% (41/147). One-year survivors and non-survivors did not differ in the following characteristics age, gender, sodium level at hospital discharge, ejection fraction, NYHA Class, basic and instrumental activities of daily living, and the presence of a geriatric risk profile. There was a significant lower systolic blood pressure at discharge in non-survivors compared to one-year-survivors (mean 125.26 mmHg vs. 137.59 mmHg). Non-survivors had more severe underlying comorbidities according to the age adjusted Charlson Comorbidity index (CCI) (mean 8.80 vs. 7.40).Both logistic and Cox regression showed a higher risk and rate of mortality with decreasing systolic blood pressure at discharge (OR 0.963, p=0.001 and HR 0.970, p<0.001) and with increasing CCI (OR 1.344, p=0.002 and HR 1.269, p=0.001); the other variables were not significantly related.

CONCLUSION:

Lower blood pressure and more severe comorbidities, but not functionality nor the presence of a geriatric risk profile, are related to one-year mortality in older, in-hospital heart failure patients.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evaluación Geriátrica / Insuficiencia Cardíaca Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Acta Clin Belg Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Evaluación Geriátrica / Insuficiencia Cardíaca Límite: Aged / Aged80 / Female / Humans / Male Idioma: En Revista: Acta Clin Belg Año: 2024 Tipo del documento: Article País de afiliación: Bélgica Pais de publicación: Reino Unido