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Doppler Ultrasound and Resistive Indices in the Diagnosis of Ureteropelvic Junction Obstruction in the Pediatric Population.
Meyers, Mariana L; Walker, Jonathan; Sevick, Carter; Beltran, Gemma G; Vemulakonda, Vijaya M.
Afiliación
  • Meyers ML; Pediatric Radiology Department, Children's Hospital Colorado, Aurora, Colorado, USA.
  • Walker J; Children's Hospital Colorado, Aurora, Colorado, USA.
  • Sevick C; University of Colorado School of Medicine, Aurora, Colorado, USA.
  • Beltran GG; Children's Hospital Colorado, Aurora, Colorado, USA.
  • Vemulakonda VM; University of Colorado School of Medicine, Aurora, Colorado, USA.
J Ultrasound Med ; 43(9): 1595-1604, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38752367
ABSTRACT

OBJECTIVES:

Mercapto acetyl tri-glycine renogram (MAG3) scan has been the gold standard assessment of pediatric ureteropelvic junction obstruction (UPJO) but requires intravenous access and radiation exposure. While Doppler ultrasound measurements of resistive indices (RI) of the arcuate arteries have been proposed as an alternative assessment of obstruction, they have not been widely adopted in the pediatric population. We hypothesized that RI of the main renal artery (RA) is more strongly correlated with MAG3 findings than arcuate RI.

METHODS:

Pediatric patients with unilateral Society for Fetal Urology grade 3-4 hydronephrosis undergoing concomitant RUS and MAG3 were recruited. Doppler ultrasound peak systolic velocity (PSV); RI of bilateral RA at the origin, middle, and hilum; and RI of the superior, middle, and lower pole arcuate arteries were obtained. MAG3 differential renal function (DRF) and T½ were recorded. Differences in RI measurements (DRI) between the affected and normal kidney were calculated and compared with DRF and T½.

RESULTS:

31 patients (median 4.6-month-old) were enrolled. Only RA RI at the origin differed between affected and normal kidneys (p < .001). DRI RA at the origin showed weak evidence for an association with MAG3 DRF < 40% (p .07). DRI was not associated with T½ > 20 minutes.

CONCLUSION:

There was weak evidence for an association between RA DRI at the origin and DRF but not with T½. These findings suggest that RA DRI may provide additional data in the evaluation of patients with UPJO to tailor the use of MAG3 and associated risk of radiation exposure to those patients most at risk for concomitant renal function impairment.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción Ureteral / Ultrasonografía Doppler Límite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Ultrasound Med Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Obstrucción Ureteral / Ultrasonografía Doppler Límite: Child / Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Ultrasound Med Año: 2024 Tipo del documento: Article País de afiliación: Estados Unidos Pais de publicación: Reino Unido