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Peripapillary pachychoroid syndrome treated with dexamethasone implant: A case report.
Feo, Alessandro; La Spina, Carlo; Romano, Mario R; Querques, Giuseppe; Panico, Edoardo; Panico, Claudio; Del Turco, Claudia.
Afiliación
  • Feo A; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.
  • La Spina C; Eye Unit, Humanitas-Gradenigo Hospital, Turin, Italy.
  • Romano MR; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.
  • Querques G; Department of Ophthalmology, Eye Unit Humanitas Gavazzeni-Castelli, Via Mazzini 11, Bergamo, Italy.
  • Panico E; Department of Ophthalmology, IRCCS Ospedale San Raffaele, Vita-Salute University, Milan, Italy.
  • Panico C; Eye Unit, Humanitas-Gradenigo Hospital, Turin, Italy.
  • Del Turco C; Eye Unit, Humanitas-Gradenigo Hospital, Turin, Italy.
Eur J Ophthalmol ; 34(5): NP59-NP64, 2024 Sep.
Article en En | MEDLINE | ID: mdl-38751124
ABSTRACT

PURPOSE:

To describe a case of peripapillary pachychoroid syndrome (PPS) in a diabetic patient with cystoid macular edema (CME), treated with intravitreal dexamethasone implant (IDI) injection. This report also illustrates the history of the disease after repeated IDI and dexamethasone topical treatment.

METHODS:

A case report.

RESULTS:

A 77-year old male patient with PPS and good diabetic control was treated with dexamethasone implant for CME. After an initial morphofunctional improvement associated with a first IDI, the disease relapsed after the second dexamethasone implant injection. This was associated with a significant increase in both intraretinal fluid and choroidal thickness, with subsequent visual acuity (VA) decrease. At this point, a topical dexamethasone treatment was performed and, despite a morphological improvement, VA worsened compared with baseline, likely because of anatomical damage.

CONCLUSION:

In this report, the importance of the recognition of PPS is underlined and the possible occurrence of a "rebound" effect due to repeated IDI is described.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dexametasona / Agudeza Visual / Edema Macular / Tomografía de Coherencia Óptica / Implantes de Medicamentos / Inyecciones Intravítreas / Glucocorticoides Límite: Aged / Humans / Male Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Dexametasona / Agudeza Visual / Edema Macular / Tomografía de Coherencia Óptica / Implantes de Medicamentos / Inyecciones Intravítreas / Glucocorticoides Límite: Aged / Humans / Male Idioma: En Revista: Eur J Ophthalmol Asunto de la revista: OFTALMOLOGIA Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Estados Unidos