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Periprocedural myocardial infarction after percutaneous coronary intervention and long-term mortality: a meta-analysis.
Paolucci, Luca; Mangiacapra, Fabio; Sergio, Sara; Nusca, Annunziata; Briguori, Carlo; Barbato, Emanuele; Ussia, Gian Paolo; Grigioni, Francesco.
Afiliación
  • Paolucci L; Interventional Cardiology Unit, Mediterranea Cardiocentro, Naples, Italy.
  • Mangiacapra F; Research Unit of Cardiovascular Science, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, Rome 00128, Italy.
  • Sergio S; Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy.
  • Nusca A; Research Unit of Cardiovascular Science, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, Rome 00128, Italy.
  • Briguori C; Research Unit of Cardiovascular Science, Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Via Alvaro del Portillo 21, Rome 00128, Italy.
  • Barbato E; Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo 200, Rome 00128, Italy.
  • Ussia GP; Interventional Cardiology Unit, Mediterranea Cardiocentro, Naples, Italy.
  • Grigioni F; Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.
Eur Heart J ; 45(33): 3018-3027, 2024 Sep 01.
Article en En | MEDLINE | ID: mdl-38742545
ABSTRACT
BACKGROUND AND

AIMS:

Conflicting data are available regarding the association between periprocedural myocardial infarction (PMI) and mortality following percutaneous coronary intervention. The purpose of this study was to evaluate the incidence and prognostic implication of PMI according to the Universal Definition of Myocardial Infarction (UDMI), the Academic Research Consortium (ARC)-2 definition, and the Society for Cardiovascular Angiography and Interventions (SCAI) definition.

METHODS:

Studies reporting adjusted effect estimates were systematically searched. The primary outcome was all-cause death, while cardiac death was included as a secondary outcome. Studies defining PMI according to biomarker elevation without further evidence of myocardial ischaemia ('ancillary criteria') were included and reported as 'definition-like'. Data were pooled in a random-effect model.

RESULTS:

A total of 19 studies and 109 568 patients were included. The incidence of PMI was progressively lower across the UDMI, ARC-2, and SCAI definitions. All PMI definitions were independently associated with all-cause mortality [UDMI hazard ratio (HR) 1.61, 95% confidence interval (CI) 1.32-1.97; I2 34%; ARC-2 HR 2.07, 95% CI 1.40-3.08, I2 0%; SCAI HR 3.24, 95% CI 2.36-4.44, I2 78%]. Including ancillary criteria in the PMI definitions were associated with an increased prognostic performance in the UDMI but not in the SCAI definition. Data were consistent after evaluation of major sources of heterogeneity.

CONCLUSIONS:

All currently available international definitions of PMI are associated with an increased risk of all-cause death after percutaneous coronary intervention. The magnitude of this latter association varies according to the sensitivity and prognostic relevance of each definition.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio Límite: Female / Humans / Male Idioma: En Revista: Eur Heart J Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Intervención Coronaria Percutánea / Infarto del Miocardio Límite: Female / Humans / Male Idioma: En Revista: Eur Heart J Año: 2024 Tipo del documento: Article País de afiliación: Italia Pais de publicación: Reino Unido