[Evaluation of leukemogenic and immunogenic properties of leukemic cells modified by neuraminidase of non-cholera Vibrios on the model of Rauscher leukemia]. / Otsenka leikemogennykh i immunogennykh svoistv modifitsirovannykh neiraminidazoi nekholernykh vibrionov leikoznykh kletok na modeli leikoza Raushera.
Eksp Onkol
; 7(2): 56-60, 1985.
Article
en Ru
| MEDLINE
| ID: mdl-3874054
The leukemogenic activity of modified leukemic cells was studied in experiments on the 385 BALB/c mice with Rauscher leukemia by transplantation of different amount of treated cells. Immunogenicity of modified leukemic cells was estimated under conditions of three-fold immunization of animals 2 days later by the cells dose equal to 1.10(6) which began 24 h after the leukemia transplantation. The effect of immunotherapy of neuraminidase-modified leukemic cells results in elongation of animal lifetime, presence of less pronounced changes in the peripheral blood and spleen as well as in stimulation of cell immunity factors.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Leucemia Experimental
/
Inmunoterapia
/
Neuraminidasa
Tipo de estudio:
Etiology_studies
/
Prognostic_studies
Límite:
Animals
Idioma:
Ru
Revista:
Eksp Onkol
Año:
1985
Tipo del documento:
Article
Pais de publicación:
Ucrania