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Study on disease activity of immunological disorders to correlate with thyroid function and other associated correlations.
Pawar, Akash; Joshi, Prakash; Singhai, Abhishek.
Afiliación
  • Pawar A; Department of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
  • Joshi P; Department of Medicine, Sri Aurobindo Institute of Medical Sciences and PGI, Indore, Madhya Pradesh, India.
  • Singhai A; Department of General Medicine, AIIMS, Bhopal, Madhya Pradesh, India.
J Family Med Prim Care ; 13(3): 896-902, 2024 Mar.
Article en En | MEDLINE | ID: mdl-38736834
ABSTRACT

Background:

Organ-specific immunological disorders involving organ/gland like the thyroid, liver, muscles, pancreas, etc., is a result of autoimmunity which can be with or without association with systemic immunological disorders. The thyroid gland is most commonly involved. We evaluated thyroid dysfunction and ESR among various immunological disorders and their correlation with disease activity and hemoglobin respectively. Material and

Methods:

A cross-sectional/observational study was conducted by including 110 patients with different immunological disorders who came in as in-patients and outpatients in our institute for 18 months and various data were collected and evaluated to analyze the targeted parameters among the study group.

Results:

We found a positive correlation between disease activity and thyroid dysfunction in different immunological disorders (only in Rheumatoid arthritis [P = 0.004) and Systemic lupus erythematosus (0.009) and not in other immunological disorders] among the study group. A positive correlation was found between ESR (Mean value - 19.63 and Standard Deviation (SD) - 09.473) and disease activity (only in Rheumatoid arthritis P = 0.0001) where a negative correlation was found between ESR and Hemoglobin (Mean value - 11.07 and SD - 01.91 (P = 0.001) in patients under study.

Conclusion:

Our study demonstrated a positive correlation between thyroid dysfunction and ESR with disease activity, whereas demonstrated a negative correlation between ESR and Hemoglobin in patients with various immunological disorders under study.
Palabras clave

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Family Med Prim Care Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Family Med Prim Care Año: 2024 Tipo del documento: Article País de afiliación: India Pais de publicación: India