Determinants of Health-Related Quality of Life in Outpatients with Myocardial Infarction.

Jarab, Anan S; Mansour, Razan Z; Muflih, Suhaib; Al-Qerem, Walid; Abu Heshmeh, Shrouq R; Alzoubi, Karem H; Al Hamarneh, Yazid N; Aburuz, Salah; Al Momany, Enaam M

Jarab, Anan S; Mansour, Razan Z; Muflih, Suhaib; Al-Qerem, Walid; Abu Heshmeh, Shrouq R; Alzoubi, Karem H; Al Hamarneh, Yazid N; Aburuz, Salah; Al Momany, Enaam M.

Afiliación

Jarab AS; College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.
Mansour RZ; AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates.
Muflih S; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Al-Qerem W; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Abu Heshmeh SR; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Alzoubi KH; Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, 11733, Jordan.
Al Hamarneh YN; Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Aburuz S; Department of Pharmacy Practice and Pharmacotherapeutics, University of Sharjah, Sharjah, United Arab Emirates.
Al Momany EM; Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

J Multidiscip Healthc ; 17: 2133-2145, 2024.

Article en En | MEDLINE | ID: mdl-38736536

ABSTRACT

ABSTRACT

Background:

The health-related quality of life (HRQOL) of patients with myocardial infarction (MI) is suboptimal because of the disease's life-threatening nature, the requirement for long-term lifestyle modifications, and the treatment regimens following MI. This study aimed to evaluate HRQOL and its associated factors in MI patients. Material and

Methods:

This study was conducted on patients with MI who attended the outpatient cardiology clinic at a major teaching hospital in Jordan. The EQ-5D-3L questionnaire was used to assess HRQOL of the study participants. Quantile regression analysis was conducted to identify the variables associated with HRQOL.

Results:

The study included 333 patients with a history of MI, with a median age of 58 (57-60). The median of the total EQ-5D score was 0.65 (0.216-0.805). Regression results revealed that male patients (Coefficient= 0.110, 95%Cl (0.022-0.197), P=0.014) and not being diagnosed with diabetes (Coefficient= 0.154, 95%Cl (0.042-0.266), P=0.007) were associated with increased HRQOL. On the other hand, low income (Coefficient= -0.115, 95%Cl (-0.203 - -0.026), P=0.011), not receiving DPP-4 (Dipeptidyl Peptidase -4) inhibitors (Coefficient= -0.321 95%Cl (-0.462 - -0.180), P<0.001), and having low (Coefficient= -0.271, 95%Cl (-0.395 - -0.147), P<0.001) or moderate (Coefficient= -0.123, 95%Cl (-0.202 - -0.044), P=0.002) medication adherence was associated with decreased HRQOL.

Conclusion:

The current study demonstrated diminished HRQOL among patients with MI, highlighting the necessity of tailoring interventions to tackle medication adherence barriers in this population. Personalized interventions such as educational programs, counseling, and reminders that consider each patient's needs and circumstances can greatly enhance medication adherence and, thus, the HRQOL of MI patients. Individuals with lower income levels, female patients, and those with diabetes should be the specific targets of these interventions.

Palabras clave

EQ-5D; Jordan; factor; health-related quality of life; myocardial infarction

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: J Multidiscip Healthc Año: 2024 Tipo del documento: Article País de afiliación: Emiratos Árabes Unidos Pais de publicación: Nueva Zelanda

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