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The impact of time from ILD diagnosis to referral to the transplant center on the probability of inclusion in the transplant waiting list.
Mora-Cuesta, Víctor M; Martínez-Meñaca, Amaya; González-Fernández, Ángel; Iturbe-Fernández, David; Tello-Mena, Sandra; Izquierdo-Cuervo, Sheila; Fernández-Rozas, Sonia; Alonso-Lecue, Pilar; Cifrián-Martínez, José M.
Afiliación
  • Mora-Cuesta VM; Respiratory Department, Lung Transplant Unit, ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Avda. Valdecilla s/n. 39008, Santander, Spain. Electronic address: victormanuel.mora@scsalud.es.
  • Martínez-Meñaca A; Respiratory Department. ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Spain.
  • González-Fernández Á; Schol of Medicine, University of Cantabria, Spain.
  • Iturbe-Fernández D; Respiratory Department, Lung Transplant Unit, ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Avda. Valdecilla s/n. 39008, Santander, Spain.
  • Tello-Mena S; Respiratory Department, Lung Transplant Unit, ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Avda. Valdecilla s/n. 39008, Santander, Spain.
  • Izquierdo-Cuervo S; Respiratory Department, Lung Transplant Unit, ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Avda. Valdecilla s/n. 39008, Santander, Spain.
  • Fernández-Rozas S; Respiratory Department. ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Spain.
  • Alonso-Lecue P; Valdecilla Research Institute (IDIVAL), Spain.
  • Cifrián-Martínez JM; Respiratory Department, Lung Transplant Unit, ERN-LUNG (European Reference Network on Rare Respiratory Diseases), Marqués de Valdecilla University Hospital, Avda. Valdecilla s/n. 39008, Santander, Spain.
Heart Lung ; 67: 92-99, 2024.
Article en En | MEDLINE | ID: mdl-38735159
ABSTRACT

BACKGROUND:

Lung transplant is a therapeutic option for patients with progressive interstitial lung disease (ILD).

OBJECTIVES:

The objective of this study was to determine whether time from ILD diagnosis to referral to a transplant center influences the probability of being included in the transplant waiting list.

METHODS:

We performed a retrospective cohort study including all ILD patients evaluated as lung transplantation (LT) candidates at a lung transplant center between 01/01/2017 and 31/12/2022. The primary endpoint was the probability of being included in the lung transplant waiting list according to the time elapsed from diagnosis to referral to the transplant center.

RESULTS:

A total of 843 lung transplant requests were received, of which 367 (43.5%) were associated with ILD. Thirteen patients were excluded because they did not attend the first visit, whereas another 11 were excluded because some information was missing. As a result, our final sample was composed of 343 patients. The median time from diagnosis to referral was 29.4 (10.9 - 61.1) months. The overall probability of inclusion in the waiting list was 29.7%. By time from diagnosis to referral, the probability of inclusion in the waiting list was 48.1% for the patients referred 〈 6 months from diagnosis; 27.5% for patients referred 6 to 24 months from diagnosis; and 25.8% for patients referred 〉 24 months from diagnosis (p = 0.007).

CONCLUSIONS:

Early referral to a lung transplant center seemed to increase the probability of being included in the lung transplant waiting list. Further research is needed in this topic.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivación y Consulta / Listas de Espera / Trasplante de Pulmón / Enfermedades Pulmonares Intersticiales Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Heart Lung Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Derivación y Consulta / Listas de Espera / Trasplante de Pulmón / Enfermedades Pulmonares Intersticiales Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Heart Lung Año: 2024 Tipo del documento: Article Pais de publicación: Estados Unidos